Results 111 to 120 of about 2,633,569 (375)

Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. [PDF]

, 2003
Antagonists of alphavbeta3 and alphavbeta5 disrupt angiogenesis in response to bFGF and VEGF, respectively. Here, we show that these alphav integrins differentially contribute to sustained Ras-extracellular signal-related kinase (Ras-ERK) signaling in ...
Cheresh, David A, Frausto, Ricardo, Hood, John D, Kiosses, William B, Schwartz, Martin A   +4 more
core   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2 [PDF]

, 2018
.: The development of functional blood and lymphatic vessels requires spatio-temporal coordination of the production and release of growth factors such as vascular endothelial growth factors (VEGFs). VEGF family proteins are produced in multiple isoforms
Arn, S., Ballmer-Hofer, K., Bogucki, A., Cariolato, L., Cébe Suarez, S., Hoffmann, U., Manlius, C., Pieren, M., Wood, J.   +8 more
core  

Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target [PDF]

, 2016
Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag,
A Parenti, AJ Maloof, B Amoozgar, B Hinz, B Lundqvist, B Thylefors, BP Danysh, C Biagi, D Belotti, D Spalton, D Xu, G Duncan, G Duncan, GC Brown, IM Wormstone, IM Wormstone, IM Wormstone, IM Wormstone, IM Wormstone, J Nagata, JA Eldred, JA Eldred, JF Boyce, JL Davis, JL Kovach, K Hayashi, K Ohta, L Leishman, MA Nanavaty, N Ferrara, NI Chaudhary, NV Palejwala, O Nishi, PJ Sime, R Alon, RJ Kelly, RL Avery, RU de Iongh, S Resnikoff, SC Kavoussi, T Hara, T Hara, TM Rabsilber, W Wu, X Huang   +44 more
core   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

Supplementary FIgure S6 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway

, 2023
Dalin He, Lei Li, Guodong Zhu, Liang Liang, Zhenfeng Guan, Luke S. Chang, Yuan Chen, Shuyuan Yeh, Chawnshang Chang   +8 more
openalex   +2 more sources

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

BMC Cancer, 2019
Background In many malignancies including ovarian cancer, different angiogenic factors have been related to poor prognosis. However, data on their relations to each other or importance as a prognostic factor in ovarian cancer is missing.
Minna Sopo, Maarit Anttila, Kirsi Hämäläinen, Annukka Kivelä, Seppo Ylä-Herttuala, Veli-Matti Kosma, Leea Keski-Nisula, Hanna Sallinen   +7 more
doaj   +1 more source

Guided Bone Regeneration Membrane Materials Loaded with Chimeric Nanovesicles Promote Early Bone Defect Regeneration

Advanced Healthcare Materials, EarlyView.
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang, Yaqiong Wang, Xiaona Ning, Guichu Yue, Wenhui Zhang, Yicheng Chen, Xuelian Jia, Yu Zhang, Xiao Zhang, Zihan Lu, Simin Zhu, Fuwei Liu, Yong Zhao, Liang Kong   +13 more
wiley   +1 more source