Microneedles with Interdigitated Electrodes for In Situ Impedimetric VEGF Sensing
An electrochemical device for transdermal monitoring based on flexible polylactide microneedles with interdigitated electrodes enables continuous monitoring of vascular endothelial growth factor (VEGF) in interstitial fluid. Gold‐coated microneedles functionalized with anti‐VEGF antibodies, provide an in situ detection platform with high sensitivity ...
Ritu Das+10 more
wiley +1 more source
Oxygen, Angiogenesis, Cancer and Immune Interplay in Breast Tumor Micro-Environment: A Computational Investigation [PDF]
Breast cancer is one of the most challenging global health problems among women. This study investigates the intricate breast tumor microenvironment (TME) dynamics utilizing data from Mammary-specific Polyomavirus Middle T Antigen Overexpression mouse models (MMTV-PyMT).
arxiv
Steroid Receptors and Vertebrate Evolution [PDF]
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago. Results from sequence analyses of genomes from bacteria, yeast, plants, invertebrates and vertebrates indicate that receptors for adrenal steroids (aldosterone ...
arxiv
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1 [PDF]
B Barleon+5 more
openalex +1 more source
Current Advances of Antibacterial Biomaterials for Bone Regeneration
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong+3 more
wiley +1 more source
Vascular Endothelial Growth Factor (VEGF) Is Present in Human Breast Milk and Its Receptor Is Present on Intestinal Epithelial Cells [PDF]
Constantinos G. Siafakas+4 more
openalex +1 more source
Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui+5 more
wiley +1 more source
von Hippel-Lindau Syndrome: Target for Anti-Vascular Endothelial Growth Factor (VEGF) Receptor Therapy [PDF]
Adrian L. Harris
openalex +3 more sources
Accuracy of direct gradient sensing by cell-surface receptors [PDF]
Chemotactic cells of eukaryotic organisms are able to accurately sense shallow chemical concentration gradients using cell-surface receptors. This sensing ability is remarkable as cells must be able to spatially resolve small fractional differences in the numbers of particles randomly arriving at cell-surface receptors by diffusion.
arxiv
Tie2 Receptor Ligands, Angiopoietin-1 and Angiopoietin-2, Modulate VEGF-Induced Postnatal Neovascularization [PDF]
Takayuki Asahara+7 more
openalex +1 more source