Results 201 to 210 of about 2,633,569 (375)

Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells

Journal of Cellular Physiology, 2010
A. Miki, Katsuaki Miki, S. Ueno, Delphine M. Bonnet Wersinger, C. Berlinicke, G. Shaw, S. Usui, Yuxia Wang, D. Zack, P. Campochiaro   +9 more
semanticscholar   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Supplementary Figure Legend 1 from Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice

, 2023
Dhanalakshmi Chinnasamy, Zhiya Yu, Sid P. Kerkar, Ling Zhang, Richard A. Morgan, Nicholas P. Restifo, Steven A. Rosenberg   +6 more
openalex   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

Advanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo, Xiaomeng Jia, Shenghong Wang, Xinyu Li, Yajing Liu, Lisen Lin, Zhengkun Wang, Fujun Liu, Slawomir Wolczynski, Nafis Rahman, Jie Gao, Xuguang Du, Suk‐Ying Tsang, Jiali Liu, Wei Song, Xiangdong Li   +15 more
wiley   +1 more source

Highly efficient naked DNA delivery of a soluble form of VEGF receptor suppressed the growth of murine renal cell carcinoma.

, 2003
Hiroshi Yazawa, Takaya Murakami, Tim Back, Yasuhiro Suzuki, Lynnete Shorts, Robert H. Wiltrout, Morihiro Watanabe   +6 more
openalex   +2 more sources

VEGF and its Receptors are Expressed in a Pediatric Angiosarcoma in a Patient with Aicardi's Syndrome [PDF]

, 2000
Elizabeth R. McLaughlin, Jack L. Arbiser, Lawrence F. Brown, Sharon W. Weiss, John B. Mulliken, Antonio R. Pérez‐Atayde   +5 more
openalex   +1 more source

Soluble VEGFR‐2: an antilymphangiogenic variant of VEGF receptors

Annals of the New York Academy of Sciences, 2010
H. Pavlaković, J. Becker, R. Albuquerque, J. Wilting, J. Ambati   +4 more
semanticscholar   +1 more source

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation

Advanced Science, EarlyView.
Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao, Jiao‐Jiao Zhang, Meng‐Qi You, Han Wang, Yan Lin, Yuan Fang, Hui‐Lu Zhang, Yuan‐Yuan Qu, Qian Zhou, Meng Wang, Gang Li, Zi‐Fan Guo, Meng Xu, Jie Liu, Peng‐Cheng Lin, Yi‐Yuan Yuan, Yu Kang, Shi‐Min Zhao, Wei Xu   +18 more
wiley   +1 more source

Profiling of VEGF Receptors and Immune Checkpoints in Recurrent Respiratory Papillomatosis. [PDF]

Laryngoscope
Lam B, Miller J, Kung YJ, Wu TC, Hung CF, Roden RBS, Best SR.   +6 more
europepmc   +1 more source

Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish.

Proceedings of the National Academy of Sciences of the United States of America, 2006
Laurence D. Covassin, Jacques A Villefranc, Michael C. Kacergis, B. Weinstein, N. Lawson   +4 more
semanticscholar   +1 more source