Results 211 to 220 of about 2,468,898 (371)

Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domains of the VEGF receptors. [PDF]

Sci Adv, 2016
Michaloski JS, Redondo AR, Magalhães LS, Cambui CC, Giordano RJ.   +4 more
europepmc   +1 more source

Pharmacokinetics and interspecies scaling of a novel VEGF receptor inhibitor, SU5416 [PDF]

, 2001
Juthamas Sukbuntherng, G. Cropp, Alison L. Hannah, Gregory S. Wagner, Laura K. Shawver, Lida Antonian   +5 more
openalex   +1 more source

Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long, Chuanquan Liu, Haotian Zheng, Mingyue Wang, Hanmei Liu, Yue Liu, Zhicheng Cao, Yuzhi Sun, Qingyun Mo, Ludvig J. Backman, Jialin Zhu, Lizhi Hu, Jinlong Huang, Wei Zhang, Jialin Chen   +14 more
wiley   +1 more source

Anti-tumour activity of tivozanib, a pan-inhibitor of VEGF receptors, in therapy-resistant ovarian carcinoma cells. [PDF]

Sci Rep, 2017
Momeny M, Sabourinejad Z, Zarrinrad G, Moghaddaskho F, Eyvani H, Yousefi H, Mirshahvaladi S, Poursani EM, Barghi F, Poursheikhani A, Dardaei L, Bashash D, Ghazi-Khansari M, Tavangar SM, Dehpour AR, Yaghmaie M, Alimoghaddam K, Ghavamzadeh A, Ghaffari SH.   +18 more
europepmc   +1 more source

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

HIVEP3 cooperates with ferroptosis gene signatures to confer adverse prognosis in acute myeloid leukemia

Cancer Medicine, Volume 11, Issue 24, Page 5050-5065, December 2022., 2022
The aberrant expression pattern and prognostic implications of HIVEP3 in AML were explored and validated based on versatile bioinformatics tools. A LASSO model which combined HIVEP3 with ferroptosis regulators was created to predict the prognosis for AML patients.
Xiaoning Zhang, Xiaoyu Zhang, Kuo Liu, Wenwen Li, Jiazheng Wang, Peng Liu, Wanshan Ma   +6 more
wiley   +1 more source

Increased Vascular Endothelial Growth Factor 165 Binding to Kinase Insert Domain–Containing Receptor After Infection of Human Endothelial Cells by Recombinant Adenovirus Encoding the Vegf ₁₆₅ Gene [PDF]

, 2001
Anat Weisz, Belly Koren, Tzafra Cohen, Gera Neufeld, Tamar Kleinberger, Basil S. Lewis, Moshe Y. Flugelman   +6 more
openalex   +1 more source

CO‐Releasing Polyoxometalates Nanozyme with Gut Mucosal Immunity and Microbiota Homeostasis Remodeling Effects for Restoring Intestinal Barrier Integrity

Advanced Science, EarlyView.
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu, Qiang Zhou, Jiayu Li, Shengming Xu, Li Yu, Yinci Zhu, He Zhang, Chengge Shi, Tianci Zuo, Mengzhu Xu, Mingli Su, Yanmei Zhang, Rongdang Hu, Quazi T. H. Shubhra, Hui Deng, Xiaowen Hu, Xiaojun Cai   +16 more
wiley   +1 more source

Tumor‐associated macrophages regulate the function of cytotoxic T lymphocyte through PD‐1/PD‐L1 pathway in multiple myeloma

Cancer Medicine, Volume 11, Issue 24, Page 4838-4848, December 2022., 2022
Tumor‐associated macrophages(TAMs) are a vital constituent of the tumor microenvironment and involved in the immunological escape of vicious clonal plasma cells of myeloma patients. Our research shows that CSF1R can regulates the production of TAMs while the PD‐1/PD‐L1 pathway regulates the effect of TAMs on cytotoxic T lymphocyte. It may provide a new
Jiangbo Zhang, Zhaoyun Liu, Panpan Cao, Hao Wang, Hui Liu, Luoming Hua, Hua Xue, Rong Fu   +7 more
wiley   +1 more source

Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes

Advanced Science, EarlyView.
IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...
Yumeng Ma, Fanqiang Meng, Zhongda Lin, Yanjun Chen, Tianyu Lan, Zhaoxin Yang, Rui Diao, Xiaozhou Zhang, Qi Chen, Chi Zhang, Yishi Tian, Chanjuan Li, Wenli Fang, Xin Liang, Xudong Zhang   +14 more
wiley   +1 more source