Results 51 to 60 of about 2,650,230 (376)
Сибирский онкологический журнал, 2021 Purpose: to study the expression of vascular endothelial growth factor (vegf-a) and its receptors (vegfr-1 and vegfr-2) in renal cell carcinoma (rcc) cells and assess the effect of the expression levels of these markers on the tumor characteristics and ...
D. A. Khochenkov +7 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide. Blindness can occur from retinal detachment caused by pathologic retinal angiogenesis into the vitreous, termed intravitreal neovascularization (IVNV).
Aniket Ramshekar, M. Elizabeth Hartnett
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Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]
, 2015 Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo +2 more
core +2 more sources
Gene Expression Analysis of VEGF and Its Receptors and Assessment of Its Serum Level in Unexplained Recurrent Spontaneous Abortion [PDF]
Cell Journal, 2015 Objective: Unexplained recurrent spontaneous abortion (URSA) is one of the main complications of pregnancy which is usually defined as three or more consecutive pregnancy losses before the 20th week of gestation without a known cause.
Elham Amirchaghmaghi +5 more
doaj
A Hybrid Model of the Role of VEGF Binding in Endothelial CellMigration and Capillary Formation
Frontiers in Oncology, 2013 Vascular endothelial growth factor (VEGF) is the most studied family of soluble secreted mediators of endothelial cell migration, survival and proliferation.
Harsh eJain, Trachette eJackson
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Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin [PDF]
, 2016 Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the extracellular matrix, yet the mechanisms behind this phenomenon are unclear.
Barton, William A. +3 more
core +16 more sources
Biomolecules, 2020 Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety of cells to regulate diverse biological responses. The VEGF-A family member promotes vasculogenesis and angiogenesis, processes which are essential for vascular ...
Faheem Shaik +5 more
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Journal of Biological Chemistry, 1996 Vascular endothelial growth factor (VEGF), a potent angiogenic factor, uses two receptor tyrosine kinases, FLK/KDR and FLT, to mediate its activities. We have cross-linked I-VEGF to the cell surface of various tumor cell lines and of human umbilical vein
S. Soker +3 more
semanticscholar +1 more source
Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients [PDF]
Frontiers in Physiology, 2011 Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in VEGF signaling, we have developed an experimentally based computational model. This model describes dynamic spatial transport of VEGF,
Yasmin L Hashambhoy +9 more
openaire +4 more sources
Frontiers in Oncology, 2013 Angiogenesis, the formation of new blood vessels from existing vasculature, is important in tumor growth and metastasis. A key regulator of angiogenesis is vascular endothelial growth factor (VEGF), which has been targeted in numerous anti-angiogenic ...
Stacey D Finley +2 more
doaj +1 more source