Results 41 to 50 of about 692,007 (215)
Electric vehicles has become one of alternatives in addressing energy crisis in the field of transportation. Increasing the number of electric vehicles that are not accompanied by a proper charging station management would give negative impact either to ...
Onang Surya Nugroho +2 more
doaj
A Multifunctional Single-Phase EV On-Board Charger With a New V2V Charging Assistance Capability
This paper presents the design and implementation of a single-phase multifunctional electric-vehicle (EV) on-board charger with an advanced vehicle-to-vehicle (V2V) functionality for emergency roadside charging assistance situations. Using this function,
Seyedfoad Taghizadeh +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Vehicle anti-collision algorithm based on vehicle to vehicle communication
In order to improve the accuracy of predicting vehicle collision accidents and reduce the probability of collision accidents,vehicle anti-collision algorithm(VACA)based on vehicle to vehicle communication was proposed.According to Beidou location ...
Yourong CHEN +3 more
doaj +2 more sources
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
The energy crisis and related environmental issues due to the increasing power demand are the primary concerns in today's evolving globe. Modern energy conversion systems need dependability and scalability to overcome obstacles.
Duc Tran Duy +4 more
doaj +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source

