Results 51 to 60 of about 2,404,078 (330)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Trust in Vehicle-to-Vehicle Communication [PDF]
, 2017 In traditional Pedestrian Automatic Emergency Braking (PAEB) system, vehicles equipped with onboard sensors such as radar, camera, and infrared detect pedestrians, alert the driver and/ or automatically take actions to prevent vehicle-pedestrian ...
Dankwa, Boakye +3 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Statistical Modeling and Estimation of Censored Pathloss Data [PDF]
, 2015 Pathloss is typically modeled using a log-distance power law with a large-scale fading term that is log-normal. However, the received signal is affected by the dynamic range and noise floor of the measurement system used to sound the channel, which can ...
Abbas, Taimoor +3 more
core +2 more sources
Operation requirements for V2X communication of PLMN
Dianxin kexue, 2016 Two kinds of V2X technology were introduced briefly and several typical V2X use cases were listed.It was suggested that V2X applications should be deployed with vehicular active safety function firstly.Based on V2X communication of PLMN，operation ...
Zhengwen CHEN
doaj +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Contention-based learning MAC protocol for broadcast Vehicle-to-Vehicle Communication [PDF]
, 2017 Vehicle-to-Vehicle Communication (V2V) is an upcoming technology that can enable safer, more efficient transportation via wireless connectivity among moving cars. The key enabling technology, specifying the physical and medium access control (MAC) layers
Ali, Falah +4 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Hybrid Urban Navigation for Smart Cities
, 2017 This paper proposes a design for a hybrid, city-wide urban navigation system for moving agents demanding dedicated assistance. The hybrid system combines GPS and vehicle-to-vehicle communication from an ad-hoc network of parked cars, and RFID from fixed ...
Gilmore, Robert +3 more
core +1 more source