Results 51 to 60 of about 3,055,078 (294)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

A damper for ground wind-induced launch vehicle oscillations [PDF]

open access: yes, 1975
Prelaunch oscillatory bending deflections of the Atlas/Centaur launch vehicle are restrained by a damper mechanism mounted on the end of a horizontal boom supported from the umbilical tower. A single vertical pin on the vehicle engages the mechanism, and
Bodle, J. G., Hackley, D. S.
core   +1 more source

Forward Vehicle Collision Warning Based on Quick Camera Calibration

open access: yes, 2019
Forward Vehicle Collision Warning (FCW) is one of the most important functions for autonomous vehicles. In this procedure, vehicle detection and distance measurement are core components, requiring accurate localization and estimation.
Lu, Yuwei, Wang, Qi, Yuan, Yuan
core   +1 more source

Car collision avoidance with velocity obstacle approach [PDF]

open access: yes, 2019
The obstacle avoidance maneuver is required for an autonomous vehicle. It is essential to define the system's performance by evaluating the minimum reaction times of the vehicle and analyzing the probability of success of the avoiding operation.
Antonelli, Dario   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Research on Application of Photothermal Imaging Technology in Urban Rail Transit Vehicle Intelligent Operation and Maintenance

open access: yesChengshi guidao jiaotong yanjiu
[Objective] At present, the lack of monitoring means for the operation status of key components such as axle boxes, gearboxes, and traction motors in the daily operation of urban rail transit trains, makes it impossible to realize the fault early warning
ZHANG Jianhua
doaj   +1 more source

Increasing the Quality of Transient Processes in the Vehicle Transmission

open access: yesНаука и техника, 2019
The paper shows results of an experimental and theoretical study of dynamic processes in the vehicle transmission after kinematic alignment of elements during gearshifts. The purpose of the research is increasing the quality of transient processes in the
A. Taratorkin   +2 more
doaj   +1 more source

A data collection scheme for identification of parameters in a driver model [PDF]

open access: yes, 1981
A high gain steering controller to compensate for limitations in a handicapped driver's range of motion is employed when adapting vehicle to his use. A driver/vehicle system can become unstable as vehicle speed is increased, therefore it is desirable to ...
Mcdermott, M., Mooring, B. W., Su, J. M.
core   +1 more source

Probabilistically safe vehicle control in a hostile environment [PDF]

open access: yes, 2011
In this paper we present an approach to control a vehicle in a hostile environment with static obstacles and moving adversaries. The vehicle is required to satisfy a mission objective expressed as a temporal logic specification over a set of properties ...
Belta, Calin   +4 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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