Results 91 to 100 of about 1,977,325 (303)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Measurement report: Insight into greenhouse gas emission characteristics of light-duty vehicles in China in the context of technological innovation [PDF]

Atmospheric Chemistry and Physics
Greenhouse gas (GHG) emissions represent a pivotal driver of global climate change, with vehicular emissions, particularly from light-duty vehicles, emerging as a prominent source of GHGs.
X. Yang, X. Yang, J. Ke, J. Ke, Z. Huang, Z. Huang, Y. Wen, D. Yin, Z. Jiang, Z. Yue, Y. Wang, Y. Wang, S. Liao, H. Yin, H. Yin, Y. Ding, Y. Ding   +16 more
doaj   +1 more source

Vehicle Stability Control

, 2022
Vehicle Stability Control (VSC) adalah sebuah fitur keamanan mobil yang diciptakan untuk mendeteksi dan mencegah overster, understerr dan sliding pada ban mobil saat mobil melaju di tikungan atau saat tergelincir. Teknologi ini di ciptakan pada akhir 1980-an, berkolaborasi dengan Daimler AG dan perusahaan induk Mercedes-Benz. Kemudian, pada tahun 1992,
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Fortifying casein phosphopeptides and Ca in wheat reduces the As, Cd, and Pb bioavailability based on a mouse model: Calcium and phosphate transporters and gut microbiota

Soil & Environmental Health
Reducing the oral bioavailability of metal contaminants including As, Cd, and Pb in foods can protect human health. Studies showed reduced metal bioavailability with elevated Ca and Fe intake; however, the effectiveness of enhancing food Ca and Fe ...
Sheng-Zhi Chen, Xin-Ying Lin, Rong-Yue Xue, Xu Duan, Dong-Mei Zhou, Lena Q. Ma, Hong-Bo Li   +6 more
doaj   +1 more source

Advances in Intelligent Vehicle Control. [PDF]

Sensors (Basel), 2022
Cabrera JA.
europepmc   +1 more source

Research study: Space vehicle control systems [PDF]

From the control point of view, spacecraft are classified into two main groups: those for which the spacecraft is fully defined before the control system is designed; and those for which the control system must be specified before certain interchangeable
Likins, P. W., Longman, R. W.
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source