Results 51 to 60 of about 1,977,325 (303)

Modeling of occupant behavior under lateral vehicle motion (Proposing of control laws based on human posture control mechanism and experimental validation)

Nihon Kikai Gakkai ronbunshu, 2022
To achieve simple and accurate modeling of human-like behavior with the aim of realizing a model-based design (MBD) methodology incorporating vehicle occupants, this research applied a simplified two-mass system for the upper body of a vehicle occupant ...
Tetsu YASUI, Hideki SUGIURA, Eiichi ONO
doaj   +1 more source

Integrated controls/structures study of advanced space systems [PDF]

, 1982
A cost tradeoff is postulated for a stiff structure utilizing minimal controls (and control expense) to point and stabilize the vehicle. Extra costs for a stiff structure are caused by weight, packaging size, etc. Likewise, a more flexible vehicle should
Cunningham, T. B., Greene, C. S.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

MCTS-Based Policy Improvement for Reinforcement Learning

Machine Learning and Knowledge Extraction
Curriculum Learning (CL) is a potent field in Machine Learning that provides several excellent techniques for enhancing the performance of the training process given the same data points, regardless of the training method used.
György Csippán, István Péter, Bálint Kővári, Tamás Bécsi   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Design Framework for Achieving Guarantees with Learning-Based Observers

Energies, 2021
The paper proposes a novel framework for state observer design, in which learning-based observers are incorporated. The aim of the method is to provide a framework, which is able to guarantee the limitation of the observation error, even if the error of ...
Balázs Németh, Tamás Hegedűs, Péter Gáspár   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Variable Horizon Model Predictive Control for Magnetorheological Semi-Active Suspension with Air Springs

Sensors
To improve the characteristics of traditional model predictive control (MPC) semi-active suspension that cannot achieve the optimal suspension control effect under different conditions, a variable horizon model predictive control (VHMPC) method is ...
Gang Li, Lin Zhong, Wenjun Sun, Shaohua Zhang, Qianjie Liu, Qingsheng Huang, Guoliang Hu   +6 more
doaj   +1 more source

An Energy Efficient Control Strategy for Electric Vehicle Driven by In-Wheel-Motors Based on Discrete Adaptive Sliding Mode Control

Chinese Journal of Mechanical Engineering, 2023
This paper presents an energy-efficient control strategy for electric vehicles (EVs) driven by in-wheel-motors (IWMs) based on discrete adaptive sliding mode control (DASMC).
Han Zhang, Changzhi Zhou, Chunyan Wang, Wanzhong Zhao   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source