Results 51 to 60 of about 509,429 (267)

Guided Experience Prioritization for Continuous Reinforcement Learning

IEEE Access
A primary limiting factor in modern deep learning is the availability of computational resources, a constraint that becomes particularly pronounced in the context of complex reinforcement learning tasks.
Istvan Gellert Knab, Tamas Becsi, Balint Kovari   +2 more
doaj   +1 more source

On the stabilization of leading-edge vortices with different reduced frequencies over finite-aspect-ratio pitch-up wings

AIP Advances, 2020
An implicit large-eddy simulation method is used to numerically simulate the flowfield around a finite-span rectangular wing in pitch motion. The effect of the reduced frequency (k) on the stability of the leading-edge vortex (LEV) is studied.
JiaoLong Zhang, Jun Hu, Yong Yu, HaiBin Xuan   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Failure of the three-way catalyst (TWC) introduces “super emitters”

Environment International
Vehicle exhaust is one of the major organic sources in urban areas. Old taxis equipped with failed three-way catalysts (TWCs) have been regarded as “super emitters”. Compressed natural gas (CNG) is a regular substitution fuel for gasoline in taxis.
Xinping Yang, Miao Tian, Yunjing Wang, Kai Song, Kai Li, Jiaju Liu, Yi Wen, Junfang Wang, Hang Yin, Yan Ding   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Voxel self-attention and center-point for 3D object detector

iScience
Summary: With the advancement of autonomous driving, the industrial demand for 3D object detection has continuously increased, leading to the development of anchor-based LiDAR object detectors reliant on convolutional neural networks (CNN).
Likang Fan, Jie Cao, Xulei Liu, Xianyong Li, Liting Deng, Hongwei Sun, Yiqiang Peng   +6 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A comprehensive survey on RGB-D-based human action recognition: algorithms, datasets, and popular applications

EURASIP Journal on Image and Video Processing
Due to the rapid advances in computer vision and deep learning, human action recognition has become one of the most important representative tasks for video understanding.
Yumin Zhang, Yanyong Wang
doaj   +1 more source

A Driving-Preference-Aware Framework for Vehicle Lane Change Prediction

Sensors
With the development of intelligent connected vehicle and artificial intelligence technologies, mixed traffic scenarios where autonomous and human-driven vehicles coexist are becoming increasingly common.
Ying Lyu, Yulin Wang, Huan Liu, Xiaoyu Dong, Yifan He, Yilong Ren   +5 more
doaj   +1 more source