Results 71 to 80 of about 260,789 (262)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

A Study on Real-Time Detection Method of Lane and Vehicle for Lane Change Assistant System Using Vision System on Highway

Engineering Science and Technology, an International Journal, 2018
In this work, we introduce an approach to detect information about lane and vehicle for the driver assistance system, or the lane change assistant system. Most previous research works could only detect the lanes or vehicles separately.
VanQuang Nguyen, Heungsuk Kim, SeoChang Jun, Kwangsuck Boo   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Empty Vehicle Detection with Video Analytics [PDF]

, 2013
An important issue to be addressed in transit security, in particular for driverless metro, is the assurance that a vehicle is empty before it returns to the depot. Customer specifications in recent tenders require that an automatic empty vehicle detector is provided. That improves system security since it prevents voluntary (e.g. in case of thieves or
Francesco Buemi, Mariana Esposito, Francesco Flammini, Nicola Mazzocca, Concetta Pragliola, Marcella Spirito   +5 more
openaire   +4 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Research on Speed Limit Protection System of Urban Rail Transit Engineering Equipment

机车电传动, 2020
Taking the project of metro network rail detection vehicle as an example, the speed limit protection mode of metro was studied. The principle, function, hardware composition and system protection level of adding speed limit protection system on the basis
Jianing DAI, Heliang HUANG, Chao YE
doaj  

Front-Vehicle Detection in Video Images Based on Temporal and Spatial Characteristics

Sensors, 2019
Assisted driving and unmanned driving have been areas of focus for both industry and academia. Front-vehicle detection technology, a key component of both types of driving, has also attracted great interest from researchers.
Bo Yang, Sheng Zhang, Yan Tian, Bijun Li
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A review of research on vehicle detection in adverse weather environments

Journal of Traffic and Transportation Engineering (English ed. Online)
Real-time vehicle detection in adverse weather environments is highly important for improving the level of vehicle intelligence and reducing the occurrence of traffic accidents.
Sheng Feng, Xueying Cai, Limin Li, Weixing Wang, Senang Ying   +4 more
doaj   +1 more source