Results 131 to 140 of about 419,064 (300)
Vehicle-to-Grid - What is the Benefit for a Sustainable Mobility? [PDF]
The demand for vehicles in industrialised countries is dropping and the growth rate in developing countries is slowing down rapidly. Driver of this evolution is evidently the current crisis but also the expectation that in the long run oil will not be ...
Guy Fournier +2 more
core
Advanced Science, EarlyView.An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
Advanced Science, EarlyView.The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang +16 more
wiley +1 more source
BatteriesThe lithium-plating phenomenon induced by low-temperature fast charging of lithium-ion batteries severely compromises their performance and safety. However, current lithium-plating detection methods predominantly rely on complex hardware systems with ...
Letong Li +6 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Design and evaluation of a toroidal wheel for planetary rovers [PDF]
The inverted toroidal wheel concept was perceived, mathematically quantified, and experimentally verified. The wheel design has a number of important characteristics, namely; (1) the low footprint pressures required for Mars exploration (0.5 to 1.0 psi);
Koskol, J., Yerazunis, S. W.
core +1 more source
Advanced Science, EarlyView.Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl +27 more
wiley +1 more source
Advanced Science, EarlyView.TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
The Vehicle as Mobile Sensor in a Collaborative Network. [PDF]
, 2015 The global increase in vehicle numbers and resulting traffic flow, especially in urban areas, presents a growing challenge to governments and local authorities in terms of road infra-structure and journey logistics. A growing awareness of the harmful effects of vehicle emissions and some social issues in terms of time spent travelling and in vehicles ...
openaire +1 more source
Advanced Science, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source