Results 201 to 210 of about 4,608,264 (343)

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Camera Configuration for Wearable Electronic Travel Aids Supporting Urban Mobility of Visually Impaired People. [PDF]

Sensors (Basel)
Li Y, Zheng J, Zhao J, Huang X, Liu Y, Wang C, Xu J, Xu S.   +7 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Rationale and design of the AutoHealth study: prospective clinical validation of continuous multimodal in-vehicle health monitoring in real-world mobility. [PDF]

Eur Heart J Digit Health
Naumann D, Amler T, Schoeppenthau D, Holzmann S, Preißinger J, Franz M, Hinrichs N, Schoenrath F, Meyer A.   +8 more
europepmc   +1 more source

Intrinsic Superprotonic Conduction in Metal‐Free Hydrogen‐Bonded Organic–Inorganic Frameworks

Advanced Science, EarlyView.
A simple hybridization strategy yields a suite of metal‐free hydrogen‐bonded organic‐inorganic frameworks (HOIFs) with dense, uninterrupted hydrogen‐bonded networks that possess intrinsically high superprotonic conductivity, establishing a versatile and scalable platform for high‐performance solid‐state proton conductors.
Jin Chen, Yongqiang Cheng, Simon J. Teat, Gobin Raj Acharya, Roknuzzaman Roknuzzaman, Wensong Yu, Yucong Xia, Weston C. Swallow, Xiaoying Huang, Xiaodong Yang, Thomas J. Emge, Kui Tan, Andrew J. Nieuwkoop, Lawrence J. Williams, Jing Li   +14 more
wiley   +1 more source

Comprehensive Driving Assessment to Enable Driving Resumption in Adults Recovering From Critical Illness: A Prospective Cohort Study. [PDF]

Crit Care Med
Apps C, Brooks K, Radcliffe G, Mahon K, Morris PH, Saunders G, Giles M, Homden L, Gregory J, O'Shea P, Gager M, Keating L, Grimadell-Jones A, Pearson L, Sanderson B, Slack A, Vollmer H, Susser K, Shankar-Hari M, Pattison N, Rose L, Meyer J.   +21 more
europepmc   +1 more source

Architected Spatially Deterministic Multiscale Phase Segregation in Block Copolymer Composites for Augmented Radiative Cooling

Advanced Science, EarlyView.
Multiscale phase segregation in block copolymers enables spatially deterministic structuring from molecular to macroscopic scales, decoupling solar scattering and infrared emission for augmented radiative cooling. ABSTRACT Passive radiative cooling, which reflects solar irradiation while emitting heat through the atmospheric window, provides a ...
Mingxin Feng, Feiyang Zhou, Haoran Cai, Wenchao Zhai, Shuangjiang Feng, Yanmei Liu, Xiaohai Bu, Man He, Dudong Feng, Shuang Liang, Yuming Zhou   +10 more
wiley   +1 more source

The role of a deployed British Army dental team on exercise Immediate Response 24. [PDF]

Br Dent J
Kandhari S, Harper C, Davies T.
europepmc   +1 more source

Ultralow‐Energy Analog Reservoir Computing via Reconfigurable 2‐Transistor Memory

Advanced Science, EarlyView.
This work presents a reconfigurable reservoir‐computing platform based on an oxide InSnZnO two‐transistor cell in which a hold bias selects volatile relaxation for the reservoir or quasi‐non‐volatile multilevel storage for the readout. Multi‐level hold‐bias kernel tune relaxation currents to generate diverse time constants, enriching reservoir states ...
Jeong‐Min Park, Yeong‐In Kim, Jeong Hyun Yoon, Sein Lee, Wooho Ham, Dongyun Lee, Junseo Lee, Dongwook Shin, Kyung Jun Park, Seok Daniel Namgung, Min‐Kyu Song, Jang‐Yeon Kwon   +11 more
wiley   +1 more source