Results 141 to 150 of about 903,323 (287)
Journal of Applied Toxicology, EarlyView.ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao +8 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao +6 more
wiley +1 more source
Computer simulation of a series and parallel hybrid electric vehicle [PDF]
, 1998 Although the internal combustion engine (ICE) vehicle is the most popular vehicle type in the world it has serious problems relating to its exhaust emissions and the limitation of petroleum resource.
Lee, Wonhee
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Lonely and Sick: The Role of Social Media in Consumer Practices of Relief
Psychology &Marketing, EarlyView.ABSTRACT Loneliness is increasingly recognized as a major mental health concern, yet the role of social media in alleviating it remains poorly understood. This study asks how social media help consumers cope with loneliness amid chronic illness. Focusing on women living with endometriosis, an under‐recognized and often stigmatized condition marked by ...
Beatrice Medici +2 more
wiley +1 more source
Truck overloading study in developing countries and strategies to minimize its impact [PDF]
, 2008 Overloading truck traffic is an untenable problem around the world. The occurrence of overloaded truck traffic can be evidence of rapid development of an economy.
Chan, Ying Chuen (Maple)
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Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
International Journal of Mechanical System Dynamics, EarlyView.ABSTRACT Early‐stage hydrodynamic assessment of slender multihull vessels is challenged by limited geometric maturity, uncertain propulsion integration, and strong sensitivity to operating conditions. Under such constraints, reliance on a single analytical or numerical method may lead to misleading design decisions due to oversimplification or ...
Chairat Napasaksri +4 more
wiley +1 more source
Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis
Phytotherapy Research, EarlyView.BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo +11 more
wiley +1 more source
Commercial goods and passenger carrying vehicles
, 2016 The Driver & Vehicle Agency (DVA) has produced this Guide to explain the responsibilities and systems involved in maintaining vehicles in a roadworthy condition, regardless of operating conditions, fleet size or vehicle type.
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Phytotherapy Research, EarlyView.PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu +6 more
wiley +1 more source