Results 151 to 160 of about 903,323 (287)
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source
Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao +6 more
wiley +1 more source
Abstract The Yamuna River, one of India's most significant river systems and the largest tributary of the Ganges River, serves critical ecological, socio‐economic, and cultural functions. However, rapid urbanization, industrialization, and intensive agriculture have severely degraded its water quality, resulting in extensive pollution with untreated ...
Dharmendra Kumar +6 more
wiley +1 more source
Field Investigation of Traffic Characteristics in Africa Based on an Integrated Dynamic Traffic Monitoring System. [PDF]
Chen Z +6 more
europepmc +1 more source
Automatic Measurement of Payload for Prevention of Overloading in Heavy Vehicles
Overloading of heavy vehicles results in road damage, short vehicle life, and vehicle manoeuvre difficulty. Heavy vehicle accidents may also cause serious casualties. Therefore, in addition to careful driving, overload avoidance of heavy vehicles is also an important issue in preventing traffic accidents.
openaire +1 more source
Blockchain and Food Trust: Will Consumers Pay More?
ABSTRACT Blockchain is increasingly used in agri‐food supply chains to make products more transparent and trustworthy. Yet, in countries like Italy, where certifications such as PDO, PGI, and organic labels already shape consumer confidence, its added value is still unclear.
Federico Modica +3 more
wiley +1 more source
National Policy Coherence Counts for Reducing Inequality in Global Climate and Development Agendas
ABSTRACT International institutions promote policy coherence as crucial to the effective and fair implementation of global sustainability agendas, though the evidence for its benefits is slim. We present here the first systematic cross‐country dataset on the consequences of national government efforts to promote policy coherence for vulnerable groups ...
Katherine Browne +10 more
wiley +1 more source
Advances in research on layered double hydroxides for biomedical applications
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
An econometric analysis in identifying behavioral and demographic factors associated with road crash severity in Bangladesh: Evidence from the Dhaka metropolitan city. [PDF]
Islam N +4 more
europepmc +1 more source

