Results 91 to 100 of about 2,789,801 (380)

Electric Vehicle Routing Problem

open access: yesTransportation Research Procedia, 2016
AbstractThis paper presents a general Electric Vehicle Routing Problem (EVRP) that finds the optimal routing strategy with minimal travel time cost and energy cost as well as number of EVs dispatched. This is the first EVRP model to consider the vehicle load effect on battery consumption.
Jane Lin, Ouri Wolfson, Wei Zhou
openaire   +2 more sources

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Sequential Routing-Loading Algorithm for Optimizing One-Door Container Closed-Loop Logistics Operations

open access: yesJurnal Optimasi Sistem Industri, 2020
One-door container type of vehicle is the main tool for urban logistics in Indonesia which may take the form of truck, car, or motorcycle container. The operations would be more effective when it is performed through pickup-delivery or forward-reverse ...
Paulina Kus Ariningsih   +3 more
doaj   +1 more source

CAPACITATED VEHICLE ROUTING PROBLEM

open access: yesInternational journal of research - granthaalayah, 2019
Cost of transportation of goods and services is an interesting topic in today’s society. The  Capacitated vehicle routing problem, which is been consider in this research, is one of the variants of the vehicle routing problem. In this research we develop
Ibrahim A.A   +3 more
semanticscholar   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman   +6 more
wiley   +1 more source

Optimizing petroleum redistribution in Sri Lanka: A cost-benefit transportation model

open access: yesJournal of Sustainable Development of Transport and Logistics
This case study is based on Ceylon Petroleum Corporation, Sri Lanka, the national oil and gas company and market leader in Sri Lanka. The company’s outbound logistics consists of a centralized distribution method and a redistribution process of its ...
Nuwan Jayarathna
doaj   +1 more source

A vehicle routing model with split delivery and stop nodes [PDF]

open access: yes
In this work, a new variant of the Capacitated Vehicle Routing Problem (CVRP) is presented where the vehicles cannot perform any route leg longer than a given length L (although the routes can be longer).
Francisco J. Nogales   +2 more
core  

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

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