Results 31 to 40 of about 161,659 (267)

Effects of Radial and Circumferential Flows on Power Density Improvements of Tubular Solid Oxide Fuel Cells

open access: yesEnergies, 2022
Improving the power density of SOFC stacks will accelerate their integration into mobile applications. We developed a 3D Multiphysics model validated by experimental results from early studies to examine the effect of radial and circumferential flows on ...
Abdellah Essaghouri   +6 more
doaj   +1 more source

Influence of Lithium Plating on the Mechanical Properties of Automotive High-Energy Pouch Batteries

open access: yesBatteries
Lithium plating (LP), as a specific degradation mechanism in lithium-ion batteries (LIBs), has been thoroughly investigated regarding formation conditions and potential safety hazards, but it is yet unknown how this effect influences the mechanical ...
Syed Muhammad Abbas   +6 more
doaj   +1 more source

Impact of Prolonged Electrochemical Cycling on Health Indicators of Aged Lithium-Ion Batteries for a Second-Life Use

open access: yesIEEE Access
The rising adoption of Electric Vehicles (EVs) is anticipated to significantly increase the number of used batteries entering the market. Repurposing these batteries for second-life applications is a promising solution that is technically ...
Emanuele Michelini   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Sound absorption performance of a conch-imitating cavity structure

open access: yesScience Progress, 2022
At present, in order to solve noise pollution, many experts are studying methods to improve the noise reduction performance of sound barriers and acoustic devices.
Suchao Xie   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Constructing representative driving cycle for heavy duty vehicle based on Markov chain method considering road slope

open access: yesEnergy and AI, 2021
Electrification of heavy duty vehicles (HDVs) is critical to realization of the target of carbon neutralization in the future. For most HDVs, the influence of road slope on vehicle power usually cannot be ignored due to significant road slope variation ...
Xinyi Jia   +7 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Approach for machine learning based design of experiments for occupant simulation

open access: yesFrontiers in Future Transportation, 2022
The complexity of crash scenarios in the context of vehicle safety is steadily increasing. This is especially the case on the way to mixed traffic challenges with non-automated and automated driving vehicles.
Bernd Schneider   +5 more
doaj   +1 more source

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