Results 61 to 70 of about 20,429 (312)

Optimization of scheduling scheme for self-driving vehicles by simulation algorithm

Science Progress, 2023
As a new logistics technology, self-driving electric vehicles not only improve freight efficiency but also promote energy saving and emissions reductions.
Xu Jianqiao
doaj   +1 more source

Setpoint scheduling for autonomous vehicle controllers [PDF]

2012 IEEE International Conference on Robotics and Automation, 2012
This paper considers the problem of controlling an autonomous vehicle to arrive at a specific position on a road at a given time and velocity. This ability is particularly useful for a recently introduced autonomous intersection management protocol, called AIM, which has been shown to lead to lower delays than traffic signals and stop signs ...
Tsz-Chiu Au, Michael J. Quinlan, Peter Stone 0001   +2 more
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

The Fleet Size and Mix vehicle Routing Problem with backhauls: Formulation and Set partitioning-based heuristics [PDF]

, 2013
In this paper we present a new variant of the classical Vehicle Routing Problem – the Fleet Size and Mix Vehicle Routing Problem with Backhauls (FSMVRPB). An ILP formulation of the FSMVRPB is presented.
Hajarat, Mutaz, Wassan, Niaz A., Salhi, Said   +2 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Dispatchable Potential Analysis of FCHEV Aggregator Considering Uncertainty of Charging Scheduling

Energy Science & Engineering
The analysis of the dispatchable potential of fuel‐cell hybrid electric vehicle (FCHEV) is particularly important to ensure the stable operation of the power system, but the uncertainty of vehicle owners' charging scheduling brings challenges to the ...
Guanhui Liu, Akram M. Abdurraqeeb, Abdulaziz Alkuhayli, Andres Annuk, Mohamed A. Mohamed   +4 more
doaj   +1 more source

Joint Optimization Method for Preventive Maintenance and Train Scheduling of Subway Vehicles Based on a Spatiotemporal Network Graph

Applied Sciences
To address the challenges posed by the interdependence between subway vehicle scheduling and maintenance planning, which complicates joint optimization modeling and solution processes, this study proposes a spatiotemporal network-based joint optimization
Chuanzhen Liu, Zhongwei Xu, Meng Mei, Wenqing Li   +3 more
doaj   +1 more source

Planning and Scheduling Transportation Vehicle Fleet in a Congested Traffic Environment [PDF]

Transportation is a main component of supply chain competitiveness since it plays a major role in the inbound, inter-facility, and outbound logistics. In this context, assigning and scheduling vehicle routing is a crucial management problem.
KERBACHE, Laoucine, VAN WOENSEL, Tom
core