Results 111 to 120 of about 375,389 (288)

Vehicle-to-grid regulation based on a dynamic simulation of mobility behavior [PDF]

open access: yes
This study establishes a new approach to analyzing the economic impacts of vehicle-to-grid (V2G) regulation by simulating the restrictions arising from un-predictable mobility requests by vehicle users. A case study for Germany using average daily values
Dallinger, David   +2 more
core  

Forecasting Recharging Demand to Integrate Electric Vehicle Fleets in Smart Grids [PDF]

open access: yes, 2019
Electric vehicle fleets and smart grids are two growing technologies. These technologies provided new possibilities to reduce pollution and increase energy efficiency. In this sense, electric vehicles are used as mobile loads in the power grid.
García Caro, Sebastián   +6 more
core  

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

open access: yesAdvanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su   +10 more
wiley   +1 more source

Predictive modeling of vehicle-to-grid flexibility: A bottom-up approach demonstrated for a case-study in Germany

open access: yesInternational Journal of Electrical Power & Energy Systems
Germany’s energy transition requires substantial energy storage capacity to manage grid stability and renewable energy integration. Conventional storage technologies may face limitations in meeting the projected demand, while the growing battery electric
Samuel Hasselwander   +2 more
doaj   +1 more source

Plug-In Electric Vehicles [PDF]

open access: yes, 2008
Did you know?Using electricity to power an automotive vehicle would cost the equivalent of paying less than $2.00 per gallon of gasoline at current electric prices.
Jan Mueller, Joanna Mauer
core  

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

A Neural Network-Based Model Predictive Control for a Grid-Connected Photovoltaic–Battery System with Vehicle-to-Grid and Grid-to-Vehicle Operations

open access: yesElectricity
The growing integration of photovoltaic (PV) energy systems and electric vehicles (EVs) introduces new challenges in managing energy flow within smart grid environments.
Ossama Dankar   +4 more
doaj   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

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