Results 141 to 150 of about 86,854,506 (278)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

User-driven potential for scalable, cost-effective, and flexible vehicle-to-grid resources in China. [PDF]

iScience
Han X, Wang B, Zhou S, Lu B, Yuan J, Zhang J, Li J, Wang Z.   +7 more
europepmc   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Optimisation algorithms for the charge dispatch of plug-in vehicles based on variable tariffs [PDF]

Plug-in vehicles powered by renewable energies are a viable way to reduce local and total emissions and could also support a highly efficient grid operation.
Richter, Julius, Büttner, Markus, Dallinger, David, Link, Jochen   +3 more
core  

Degradation-constrained multi-agent reinforcement learning with centralized training and decentralized execution for vehicle-to-grid optimization in renewable-dominated distribution networks. [PDF]

Sci Rep
Shiferaw Y, Kiros M, Yeneneh K, Sufe G.
europepmc   +1 more source

Equity-Aware Planning of Urban Ultra-Fast Electric Vehicle Charging Infrastructure with Spatial Graph Learning and Grid Constraints

Hansong Wu, Lu Shi, Xiaohang Gu, Tao Qian, Mingyu Fang   +4 more
openalex   +1 more source

A Bioinspired, Multimodal Soft Tactile Skin with Task‐Adaptive Perception for Intelligent Robotic Manipulation

Advanced Science, EarlyView.
Perception in robotic manipulation improves through the cooperative and complementary operation of biologically inspired multimodal tactile sensors. Receptor‐specific contribution analysis identifies which sensing modalities are required for specific tactile tasks.
Yu‐Jin Lee, Hyeonung Kang, Ju Yeon Woo, Daekyum Kim, Chang‐Soo Han   +4 more
wiley   +1 more source

Development of a solar-integrated energy management system for grid-to-vehicle and vehicle-to-grid power exchange. [PDF]

Sci Rep
Rao NVK, Krishna KB.
europepmc   +1 more source

Observability-Aware Estimation of Tradeable Vehicle-to-Grid Capacity from Heterogeneous Charger Telemetry

Róbert Štefko, Vladimír Szomosi, Marek Bobček, Jozef Király, Zsolt Čonka, Erik Chabreček   +5 more
openalex   +1 more source