Results 201 to 210 of about 375,389 (288)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

PKMζ-KIBRA interactions, molecular turnover, and memory. [PDF]

open access: yesMol Brain
Hsieh C   +6 more
europepmc   +1 more source

Impact of Cattaneo–Christov Heat and Mass Flux on MHD Hybrid Nanofluid Flow Over an Extending Surface With Convective and Mass Flux Effects

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study investigates the flow of a magnetized hybrid nanofluid over a permeable stretching surface. The mass and thermal transport within the system is regulated using the Cattaneo–Christov flux theory. The fluid is additionally subjected to thermophoresis, chemical reaction, Brownian motion, and activation energy effects.
Ebrahem A. Algehyne   +6 more
wiley   +1 more source

Prediction of Properties of Polymer Composite Formulations Using Ensemble Models With Feature Generation

open access: yesJournal of Applied Polymer Science, EarlyView.
This study develops an interpretable machine‐learning framework to predict multiple properties of polymer composites based on composition and processing variables. By combining ensemble models with composition‐based feature generation and SHAP‐based interpretation, the approach reveals composition‐property relationships and supports efficient multi ...
Dong Ryeol Shin, Sung Kwang Lee
wiley   +1 more source

Prospecting of Architectural Features Using LiDAR‐UAV Technology, Deep Neural Networks and Visualization Techniques: A Case Study in Kuélap and Cambolín (NW Peru)

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT High‐resolution and accurate synoptic images of terrestrial topography, even in densely forested areas, have proven valuable for archaeology by enabling the identification and characterization of relief patterns associated with ancient human activities. This study presents a novel approach that integrates digital terrain models (DTMs) obtained
Jhon A. Zabaleta‐Santisteban   +13 more
wiley   +1 more source

The Layout and Size of an Early Pre‐Pottery Neolithic B Small Settlement Revealed by Geophysical Prospection at Harbetsuvan Tepesi in Southeastern Anatolia

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT In Upper Mesopotamia, the transition from the Pre‐Pottery Neolithic A (PPNA) to Pre‐Pottery Neolithic B (PPNB) period, ca. 10 800–10 600 cal. BP, is marked by a series of changes in chipped stone industries, architectural forms, symbolic objects, regional distribution of settlements and long‐distance exchange networks among others.
Toshihiro Tada   +7 more
wiley   +1 more source

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