Results 131 to 140 of about 516,556 (360)

IRF8 Drives Conventional Type 1 Dendritic Cell Differentiation and CD8+ T Cell Activation to Aggravate Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan, Li Shu, Yidan Zheng, Yidong Wang, Mengsha Zheng, Jie Sun, Jiantao Fu, Zihao Zhou, Shen Song, Zhenjie Liu, Fei Li, Zhejun Cai   +11 more
wiley   +1 more source

Research on routing algorithm based on the VANET

MATEC Web of Conferences, 2016
For the characteristics of high speed mobility of nodes, frequent changes of dynamic topology and frequent interrupts of the communication links in the VANET, this paper analyzed the defect of the current mobile ad-hoc network routing protocol, and ...
AN Li, Zhao Yong Mei, Xie Peng, Wang Qiong   +3 more
doaj   +1 more source

A Novel Energy-Efficient Reservation System for Edge Computing in 6G Vehicular Ad Hoc Network. [PDF]

Sensors (Basel), 2023
Javed F, Khan ZA, Rizwan S, Shahzadi S, Chaudhry NR, Iqbal M.   +5 more
europepmc   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Improving QoS in VANET

Al-Iraqia Journal for Scientific Engineering Research
 The Vehicular Ad Hoc Network (VANET) is a novel and auspicious performance within the Intelligent Transportation Systems (ITS) field. Numerous scholars endeavoured to enhance the VANETs' Quality of Service (QoS) by creating routing procedures that were
Sukaina Hasan Mousa, Ruslan Saad Abdulrahman, Shams Mhmood Abd Ali   +2 more
doaj   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Slow Heat-Based Hybrid Simulated Annealing Algorithm in Vehicular Ad Hoc Network. [PDF]

Comput Intell Neurosci, 2023
Pagadala PK, Kumari PLS, Thakur D, Bhardwaj V, Shahid M, Buradi A, Razak A, Ketema A.   +7 more
europepmc   +1 more source

Performance evaluation of safety applications over DSRC vehicular ad hoc networks [PDF]

, 2004
Jijun Yin, Tamer ElBatt, Gavin Yeung, Bo Ryu, Stephen Habermas, Hariharan Krishnan, Timothy Talty   +6 more
openalex   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

A Multi-Tier Trust-Based Security Mechanism for Vehicular Ad-Hoc Network Communications. [PDF]

Sensors (Basel), 2022
Akwirry B, Bessis N, Malik H, McHale S.
europepmc   +1 more source