Results 81 to 90 of about 118,202 (332)

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

On the Connectivity of Vehicular Ad Hoc Network Under Various Mobility Scenarios

IEEE Access, 2017
In this paper, a new mobility metric called generalized speed factor (GSF) is proposed by extending the existing speed factor, which assumes that all vehicles have the same speed at all times.
Z. Khan, P. Fan, Sangsha Fang
semanticscholar   +1 more source

Vehicular Ad Hoc and Sensor Networks: Principals and Challenges

International Journal of Ad hoc, Sensor & Ubiquitous Computing, 2011
The rapid increase of vehicular traffic and congestion on the highways began hampering the safe and efficient movement of traffic. Consequently, year by year, we see the ascending rate of car accidents and casualties in most of the countries. Therefore, exploiting the new technologies, e.g.
G. Praveen Babu, Mohammad Jalil Piran, G. Rama Murthy   +2 more
openaire   +3 more sources

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

Advanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua, Ning Ding, Yiming Hua, Xiaoke Wang, Yu Xu, Xiangrui Qiao, Xue Shi, Ting Bai, Ying Xiong, Xiaozhen Zhuo, Chong Fan, Juan Zhou, Yue Wu, Junhui Liu, Zuyi Yuan, Ting Li   +15 more
wiley   +1 more source

Security-aware dual-hop communication for amplify-and-forward relay networks

International Journal of Distributed Sensor Networks, 2019
The authentication scheme for vehicular ad hoc networks aims to improve the security and integrity of message delivery. The base station manages a large number of vehicular nodes, so the security communications are non-trivial.
Fei Ding, Xiaojun Sun, Xiaojin Ding, Ruoyu Su, Dengyin Zhang, Hongbo Zhu   +5 more
doaj   +1 more source

IEEE Access Special Section Editorial: Resource Management in Vehicular Adhoc Networks: Energy Management, Communication Protocol and Future Applications

IEEE Access, 2017
The advancements in technology have transformed the vehicles moving around us into intelligent machines. These vehicles now have the capabilities to communicate and share useful information with each other under a communication network known as Vehicular
Tariq Umer, Mubashir Husain Rehmani, Zhi Guo Ding, Byung-Seo Kim, Samee U. Khan   +4 more
doaj   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Spatio-Temporal Network Traffic Estimation and Anomaly Detection Based on Convolutional Neural Network in Vehicular Ad-Hoc Networks

IEEE Access, 2018
Over the last decade, vehicular ad-hoc networks (VANETs) have received a greater attention in academia and industry due to their influence in intelligent transportation systems.
Laisen Nie, Yongkang Li, Xiangjie Kong
semanticscholar   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source