Results 41 to 50 of about 44,882 (282)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Dynamic broadcasting in vehicular ad hoc networks [PDF]

, 2013
Vehicular Ad hoc Network (VANET) is a subclass of mobile ad hoc networks (MANETs). VANETs provide a variety of interesting applications. Many of these applications rely on broadcasting of messages to other vehicles. The simplest broadcasting algorithm is
Abd. Razak, Shukor, Ithnin, Norafida, Karimi, Ramin, Najafzadeh, Sara   +3 more
core   +1 more source

Vehicular Ad-hoc Networks

, 2012
International Journal of Computer Science Issues (IJCSI), Volume 9, Issue 1, No 3, January ...
Maqsood, Asad, Khan, Rehanullah
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A vehicular ad hoc network privacy protection scheme without a trusted third party

International Journal of Distributed Sensor Networks, 2017
Vehicular ad hoc networks are traffic applications of the Internet of Things, which are composed of vehicle nodes, roadside units, service providers, and other components.
Xiaoliang Wang, Shuifan Li, Shujing Zhao, Zhihua Xia, Liang Bai   +4 more
doaj   +1 more source

Vehicular Ad hoc Network

, 2013
{"references": ["Saleh Yousefi, Saeed Bastani, Mahmood Fathy, \"On the Performance of Safety Message Dissemination in Vehicular Ad Hoc Networks\", IEEE Fourth European Conference on Universal Multiservice Networks, European, 2007.", "Corson, Macker, \"Informational RFC 2501 MANET Performance Issues\", January 1999.", "C2C-CC: CAR 2 CAR Communication ...
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Analysis and Modeling Experiment Performance Parameters of Routing Protocols in MANETs and VANETs [PDF]

, 2012
In this paper, a framework for experimental parameters in which Packet Delivery Ratio (PDR), effect of link duration over End-to-End Delay (E2ED) and Normalized Routing Overhead (NRO) in terms of control packets is analyzed and modeled for Mobile Ad-Hoc ...
Bibi, A., Bouk, S. H., Javaid, N., Khan, Z. A., Sagar, S., Saqib, J.   +5 more
core   +1 more source