Results 151 to 160 of about 3,794,461 (309)

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Adaptive Communication Model for QoS in Vehicular IoT Systems Using CTMC

Sensors
Vehicular Internet of Things (V-IoT) systems will be critical in advancing intelligent transportation networks because of the easy communication they make possible between vehicles, roadside infrastructure, and other network entities.
Adeel Iqbal, Tahir Khurshaid, Ali Nauman, Sung Won Kim   +3 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Hierarchical wireless framework for real-time collaborative generation and distribution of telemetry data [PDF]

, 2010
This project introduces a novel multidisciplinary approach combining Vehicular Ad Hoc Networks and Granular Computing, to the data processing and information generation problem in large urban traffic systems.
Kucukdurgut, I
core  

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Oblivious Transfer-Based Authentication and Privacy-Preserving Protocol for 5G-Enabled Vehicular Fog Computing

IEEE Access
The fast development of vehicle technology and the appearance of 5G networks have brought new opportunities as well as challenges for vehicular fog computing.
Zeyad Ghaleb Al-Mekhlafi, Saima Anwar Lashari, Jalal Mohammed Hachim Altmemi, Mahmood A. Al-Shareeda, Badiea Abdulkarem Mohammed, Amer A. Sallam, Bassam Ali Al-Qatab, Mohammad T. Alshammari, Abdulaziz M. Alayba   +8 more
doaj   +1 more source

Evaluation study of IEEE 1609.4 performance for safety and non-safety messages dissemination [PDF]

, 2014
The IEEE 1609.4 was developed to support multi-channel operation and channel switching procedure in order to provide both safety and non-safety vehicular applications.
Alaa, Mina, Abdala, Mohammed A, Al-Sherbaz, Ali   +2 more
core  

Design and Performance of Secure Geocast for Vehicular Communication

, 2010
The characteristics of vehicular communication environments and their networking and application requirements have led to the development of unique networking protocols.
Festag, A., Tielert, T., Papadimitratos, Panagiotis, Festag, Andreas, Tielert, Tessa   +4 more
core   +1 more source