Results 91 to 100 of about 24,577,898 (230)

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Interest Flooding Attacks in Named Data Networking and Mitigations: Recent Advances and Challenges

Future Internet
Named Data Networking (NDN) represents a promising Information-Centric Networking architecture that addresses limitations of traditional host-centric Internet protocols by emphasizing content names rather than host addresses for communication.
Simeon Ogunbunmi, Yu Chen, Qi Zhao, Deeraj Nagothu, Sixiao Wei, Genshe Chen, Erik Blasch   +6 more
doaj   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Prediction of Truck Fuel Consumption Based on Crossformer-LSTM Characteristic Distillation

Applied Sciences
With the increasing number of heavy-duty trucks and their high fuel consumption characteristics, reducing fuel costs has become a primary challenge for the freight industry.
Kai Du, Qingqing Shi, Jingni Song, Dan Chen, Weiyu Liu   +4 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Addressing the Effects of Low Vehicle Densities in Highly Mobile Vehicular Named-Data Networks [PDF]

, 2017
In this work, we investigate the effects of network partitions, caused by low vehicle densities, on the performance of Vehicular Named- Data Networking (VNDN) applications. We target scenarios with high mobility and propose two different solutions.
Gomes Duarte, João do Monte, Villas, Leandro, Braun, Torsten, Leandro A. Villas, Torsten Braun, Joao M. Duarte   +5 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

DeepNDN: Opportunistic Data Replication and Caching in Support of Vehicular Named Data

, 2020
Although many target applications in VANETs are information-centric, the performance of Named Data Networking (NDN) in vehicular ad-hoc networks is severely hampered by persistent network partitioning, typical of many vehicular scenarios.
Manzo, Gaetano, Ridha Souas, MariaRita Palattella, Kalogeiton, Eirini, Turcanu, Ion, Rizzo G, Braun, Torsten, Palattella, Maria Rita, Ridha Soua, Soua, Ridha, Gianluca Rizzo, Torsten Braun, Eirini Kalogeiton, Gaetano Manzo, Eirini Kalogeiton, Torsten Braun, Rizzo, Gianluca, Antonio Di Maio, Maria Rita Palattella, Gaetano Manzo, Di Maio, Antonio, Ion Turcanu, Antonio Di Maio   +22 more
core   +1 more source

Network Coding Enabled Named Data Networking Architectures [PDF]

, 2017
The volume of data traffic in the Internet has increased drastically in the last years, mostly due to data intensive applications like video streaming, file sharing, etc.. This motivates the development of new communication methods that can deal with the
Saltarin de Arco, Jonnahtan Eduardo
core   +2 more sources