Results 41 to 50 of about 127,901 (280)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Investigation of Security Threat Datasets for Intra- and Inter-Vehicular Environments

open access: yesSensors
Vehicular networks have become a critical component of modern transportation systems by facilitating communication between vehicles and infrastructure.
Achref Haddaji   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Speed Adjustment Attack on Cooperative Sensing in Cognitive Vehicular Networks

open access: yesIEEE Access, 2019
The ever-increasing demand for vehicular traffic consumption in 5G makes the problem of spectrum scarcity in vehicular networks more serious. In order to solve this problem, cognitive radio (CR) technology has been used in vehicular networks, leading to ...
Hongning Li   +3 more
doaj   +1 more source

A Comprehensive Review of Computing Paradigms, Enabling Computation Offloading and Task Execution in Vehicular Networks

open access: yesIEEE Access, 2022
Road safety, optimized traffic management, and passenger comfort have always been the primary goals of the vehicle networking research community. Advances in computer and communication technologies have made the dream of modern intelligent vehicles a ...
Abdul Waheed   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Instantly decodable network coding–assisted data dissemination for prioritized services in vehicular ad hoc networks

open access: yesInternational Journal of Distributed Sensor Networks, 2019
Safety-related and user-related applications are two main kinds of services provided in vehicular ad hoc networks. Safety-related applications have great impact on vehicles and people who participate in the transportation.
Shujuan Wang, Shuguang Lu, Qian Zhang
doaj   +1 more source

Heterogeneous Vehicular Networks [PDF]

open access: yes, 2016
This brief examines recent developments in the Heterogeneous Vehicular NETworks (HETVNETs), integrating cellular networks with Dedicated Short-Range Communication (DSRC) for meeting the communications requirements of the Intelligent Transport System (ITS)services. Along with a review of recent literature, a unified framework of the HetVNET is presented.
Zheng, Kan   +3 more
openaire   +2 more sources

An Efficient Requirement-Aware Attachment Policy for Future Millimeter Wave Vehicular Networks

open access: yes, 2019
The automotive industry is rapidly evolving towards connected and autonomous vehicles, whose ever more stringent data traffic requirements might exceed the capacity of traditional technologies for vehicular networks.
Giordani, Marco   +2 more
core   +1 more source

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