Results 51 to 60 of about 2,745,014 (253)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Shaping spectral leakage for IEEE 802.11 p vehicular communications [PDF]

open access: yes, 2014
IEEE 802.11p is a recently defined standard for the physical (PHY) and medium access control (MAC) layers for Dedicated Short-Range Communications. Four Spectrum Emission Masks (SEMs) are specified in 802.11p that are much more stringent than those for ...
Pham, Thinh H.   +5 more
core   +2 more sources

Protection of HEVC Video Delivery in Vehicular Networks with RaptorQ Codes

open access: yesThe Scientific World Journal, 2014
With future vehicles equipped with processing capability, storage, and communications, vehicular networks will become a reality. A vast number of applications will arise that will make use of this connectivity.
Pablo Piñol   +3 more
doaj   +1 more source

Software-Defined Network-Based Vehicular Networks: A Position Paper on Their Modeling and Implementation

open access: yesSensors, 2019
There is a strong devotion in the automotive industry to be part of a wider progression towards the Fifth Generation (5G) era. In-vehicle integration costs between cellular and vehicle-to-vehicle networks using Dedicated Short Range Communication could ...
Lionel Nkenyereye   +5 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

A content dissemination framework for vehicular networking [PDF]

open access: yes, 2010
Vehicular Networks are a peculiar class of wireless mobile networks in which vehicles are equipped with radio interfaces and are, therefore, able to communicate with fixed infrastructure (if available) or other vehicles.
Leontiadis, I.
core  

Mobility Models for Next Generation Wireless Networks: Ad Hoc, Vehicular and Mesh Networks

open access: yes, 2012
Mobility Models for Next Generation Wireless Networks: Ad Hoc, Vehicular and Mesh Networksprovides the reader with an overview of mobility modelling, encompassing both theoretical and practical aspects related to the challenging mobility modelling task ...
Santi P
core   +1 more source

Certificate Revocation Schemes in Vehicular Networks: A Survey

open access: yesIEEE Access, 2020
The problem of security in vehicular networks is a vital issue and attracts researchers' increasing attention for its unique characteristics, such as the vulnerability of wireless media, untrusted communication environment, and closely relationship with ...
Qianpeng Wang, Deyun Gao, Du Chen
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy