Results 101 to 110 of about 877,672 (296)

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

Three-Dimensional Modeling of the Behavior of a Blood Clot Using Different Mechanical Properties of a Blood Vessel

open access: yesMathematics
In this work, the behavior of a 3D blood clot located inside a vein under the influence of the mechanical effect of blood flow was analyzed. It has been observed that the mechanical properties of the blood vessel play an important role in the behavior of
Mantas Brusokas   +2 more
doaj   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park   +7 more
wiley   +1 more source

Complex vascular injuries of lower limbs in children

open access: yesZdravniški Vestnik, 2007
Background: Pediatric vascular trauma is rare and there is scarcity of data available to direct optimal care of these patients. Even rarer are reports of long term venous function after complex vascular repairs of lower extremities. Purpose of article is
Vojko Flis, Tomaž Tomažič
doaj  

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li   +11 more
wiley   +1 more source

Liquid‐Locked Bassanites for Scalable Fabrication of High‐Temperature Micro‐Supercapacitors Working at 300 °C

open access: yesAdvanced Functional Materials, EarlyView.
A “liquid locking” strategy is proposed and implemented for scalable printing of crack‐free bassanite ceramic frameworks with interlocking microstructures to host ionic liquids as effective electrolytes for high‐temperature micro‐supercapacitors (HT‐MSCs).
Shiqian Chen   +7 more
wiley   +1 more source

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