Results 101 to 110 of about 1,059,478 (316)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

A Leaf Modeling and Multi-Scale Remeshing Method for Visual Computation via Hierarchical Parametric Vein and Margin Representation

open access: yesFrontiers in Plant Science, 2018
This paper introduces a novel hierarchical structured representation for leaf modeling and proposes a corresponding multi-resolution remeshing method for large-scale visual computation. Leaf modeling is a very difficult and challenging problem due to the
Weiliang Wen   +5 more
doaj   +1 more source

Pulsation in the Veins [PDF]

open access: yesNature, 1885
IF Mr. Hippisley will refer to Landois' text-book, vol. i. p. 196, he will find it there stated, on the authority of Quincke, that a venous pulse occurs on rare occasions, normally, in the veins on the back of the hand and foot, when the peripheral ends of the arteries become dilated and relaxed. But it is to be remembered that the very same phenomenon
openaire   +3 more sources

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Substantiating rational parameters of a method for shrinkage ore stoping while developing thin- vein steeply inclined deposits [PDF]

open access: yes, 2018
Objective of the paper is to substantiate rational ore-stoping technique while using small wells in the context of thin-vein steeply inclined deposit mining.
Denyshchenko, Oleksandr   +3 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Portal vein grafts in hepatic transplantation [PDF]

open access: yes, 1985
Confirmation of patency of the portal vein by either ultrasound or angiography is a routine part of the evaluation of patients being considered for hepatic transplantation.
Bron, K   +3 more
core  

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