Results 41 to 50 of about 3,461,090 (232)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Journal of Engineering, 2019 Aircraft wake vortex is a sort of turbulence generated by a flying aircraft. It has attracted much attention in aviation safety area because it may cause a following aircraft to roll out of control.
Hang Gao +3 more
doaj +1 more source
Salt‐Fingering in Seasonally Ice‐Covered Lakes
Geophysical Research Letters, 2022 When ice forms on lakes, dissolved salts are rejected, which can lead to under‐ice salt finger formation. We performed a series of laboratory experiments to visualize these fingers.
J. Olsthoorn +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingAccurate estimation of river-surface flow velocity is critical for water-resources management, flood early-warning systems, and ecological modeling. Although uncrewed aerial vehicle (UAV) image velocimetry offers high efficiency and noncontact operation,
Minghu Zhang +6 more
doaj +1 more source
UAV Thrust Model Identification Using Spectrogram Analysis
Automation, 2021 This paper deals with a non-contact method to identify the aerodynamic propeller constants of the Parrot AR.Drone quadrotor. The experimental setup consists of a microphone installed in the flight arena to record audio data.
Igor Henrique Beloti Pizetta +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source