Results 31 to 40 of about 7,271 (213)

Seismic responses of isolated bridges subjected to near-fault ground motions: simple pulses vs. whole records

Frontiers in Built Environment
Velocity pulse with strong energy input is the significant feature of near-fault ground motions. Bridges close to or passing across seismic faults may suffer from higher failure risk, which is inseparable from the influence of velocity pulse.
Ying-Xin Hui, Ying-Xin Hui, Jie Wang, Jie Wang, Jia-Le Lv, Ting-Ting Xu   +5 more
doaj   +1 more source

Analysis of faulting destruction and water supply pipeline damage from the first mainshock of the February 6, 2023 Türkiye earthquake doublet[Key points]

Earthquake Science
In 2023, two consecutive earthquakes exceeding a magnitude of 7 occurred in Türkiye, causing severe casualties and economic losses. The damage to critical urban infrastructure and building structures, including highways, railroads, and water supply ...
Xiaoqing Fan, Libao Zhang, Juke Wang, Yefei Ren, Aiwen Liu   +4 more
doaj   +1 more source

Comparison of arterial stiffness indices measured by pulse wave velocity and pulse wave analysis

Blood Pressure, 2019
Objective: Arterial stiffness indices measured by pulse wave velocity and pulse wave analysis have been widely studied in different populations. Only a few small studies have been reported regarding these two measurement methods.
Hongyan Zhu, Yuan Gao, Huiling Cheng, Yichao Lu, IokFai Cheang, Dongxu Xu, Wenming Yao, Tianbao Xu, Fang Zhou, Yanli Zhou, Fang Xu, Xiangqing Kong, Xinli Li, Haifeng Zhang   +13 more
doaj   +1 more source

Pulse wave velocity in the carotid artery [PDF]

2008 IEEE Ultrasonics Symposium, 2008
The pulse wave velocity (PWV) in the carotid artery (CA) has been estimated based on ultrasound data collected by the experimental scanner RASMUS at DTU. Data is collected from one test subject using a frame rate (FR) of 4000 Hz. The influence of FRs is also investigated.
Sørensen, Gertrud Laura, Jensen, Julie Brinck, Udesen, Jesper, Holfort, Iben Kraglund, Jensen, Jørgen Arendt; id_orcid 0000-0002-7896-3136   +4 more
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Urbanization as a risk factor for aortic stiffness in a cohort in India. [PDF]

PLoS ONE, 2018
Urbanization is associated with higher prevalence of cardiovascular disease worldwide. Aortic stiffness, as measured by carotid-femoral pulse wave velocity is a validated predictor of cardiovascular disease. Our objective was to determine the association
Laura Corlin, Kevin J Lane, Jahnavi Sunderarajan, Kenneth K H Chui, Harivanza Vijayakumar, Lawrence Krakoff, Anbarasi Chandrasekaran, Sadagopan Thanikachalam, Doug Brugge, Mohan Thanikachalam   +9 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Pulse velocities in initially stressed arteries

Journal of Biomechanics, 1988
In this short paper, treating the artery as a thick walled cylindrical shell and employing the large deformation theory, an analytical expression for the pulse wave speed is obtained and the effect of lumen pressure and the axial stretch on the wave speed is discussed.
openaire   +3 more sources