Results 51 to 60 of about 129,657 (313)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Dizhen xuebao基于振动台试验，探讨了速度脉冲对综合管廊动力响应的影响，重点阐明了地震动速度脉冲特性如何影响综合管廊和周围土壤的地震行为。选取具有速度脉冲的实际地震动记录和合成的与实际地震动记录具有相同反应谱的无速度脉冲地震动时程，同时将其加速度幅值分别调整为0.10g，0.20g，0.30g作为输入，设计并开展了地震动纵向输入下的综合管廊振动台试验。基于试验数据分析了场地土体的地震反应变化规律、综合管廊结构的地震响应特征和土-结构相互作用效应。研究结果表明：① 土体在连续试验加载下结构发生变化 ...
Jian Chu +5 more
doaj +1 more source
The Effect of an Angiotensin Receptor Blocker on Arterial Stiffness in Type 2 Diabetes Mellitus Patients with Hypertension [PDF]
Diabetes & Metabolism Journal, 2011 BackgroundHypertension and type 2 diabetes mellitus are major risk factors for cardiovascular disease. This study analyzed the changes in central aortic waveforms and pulse wave velocity as well as related parameters after treatment with valsartan, an ...
Ji Hyun Kim +8 more
doaj +1 more source
Applied Sciences, 2022 In this study, the mechanical properties of normal concrete (NC) and lightweight concrete (LC) were measured upon exposure to high temperatures (20, 100, 200, 300, 500, and 700 °C).
Wonchang Kim +3 more
doaj +1 more source
, 2007 This is the post print version of the article. The official published version can be found at the link below.In a previous paper we demonstrated that the linear portion of the pressure–velocity loop (PU-loop) corresponding to early systole could be used ...
J. Feng +7 more
core +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
, 2013 We present a novel design for a surface drifter, mounted with a pulse-coherent Acoustic Doppler Current Profiler (ADCP) for measuring near-surface (depths 0.18-1 m) flows.
Mullarney, Julia C. +1 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study presents an infrared monitoring approach for direct laser interference patterning (DLIP) combined with a convolutional neural network (CNN). Thermal emission data captured during structuring are used to predict surface topography parameters.
Lukas Olawsky +5 more
wiley +1 more source