Characterizing therapeutic effects of velvet antler using different omics strategies [PDF]
Velvet antler (VA) has been widely used in traditional Chinese medicine more than thousand years. Several pharmacological properties of VA have been demonstrated, such as anti-osteoporosis, anti-osteoarthritis, anti-aging, and anti-ischemia-hypoxia ...
Shang-Tse Ho +2 more
doaj +3 more sources
Chronic Wasting Disease Prions in Elk Antler Velvet
Chronic wasting disease (CWD) is a contagious, fatal prion disease of deer and elk that continues to emerge in new locations. To explore the means by which prions are transmitted with high efficiency among cervids, we examined prion infectivity in the ...
Rachel C. Angers +8 more
doaj +3 more sources
Effects of Velvet Antler with Blood on Bone in Ovariectomized Rats [PDF]
In traditional Chinese medicine (TCM), both velvet antlers (VA) and VA blood can tonify qi, essence, and marrow, nourish the blood, and invigorate bones and tendons.
Ching-Chiung Wang +6 more
doaj +3 more sources
Velvet antler polypeptide partially rescue facet joint osteoarthritis-like phenotype in adult β-catenin conditional activation mice [PDF]
Background Wnt/β-catenin signaling pathway is closely related to osteoarthritis. In our preliminary study, β-catenin conditional activation (cAct) mice that specifically over-express β-catenin gene in cartilage chondrocyte exhibits osteoarthritis-like ...
Wan-qing Xie +7 more
doaj +2 more sources
Characteristics and Differences in the Antler Velvet Microbiota During Regeneration
The skin surface has a complex and dynamic ecosystem inhabited by a diverse microbiota. The wound formed by antler velvet shedding can naturally achieve regenerative restoration, but the changes in microbial composition that occur during antler velvet ...
Yongxiang Li +8 more
doaj +2 more sources
Effects of rumen-protected lysine on antler growth performance, fecal bacterial community, and blood gene expression in sika deer [PDF]
IntroductionVelvet antler is an important product of sika deer (Cervus nippon), and its growth is closely related to dietary amino acid supplementation.
Bo Yang +8 more
doaj +2 more sources
Effects of velvet antler polypeptide on sexual behavior and testosterone synthesis in aging male mice [PDF]
Twenty-four-month-old male C57BL/6 mice with low serum testosterone levels were used as a late-onset hypogonadism (LOH) animal model for examining the effects of velvet antler polypeptide (VAP) on sexual function and testosterone synthesis.
Zhi-Jun Zang +6 more
doaj +2 more sources
The anti-aging effect of velvet antler polypeptide is dependent on modulation of the gut microbiota and regulation of the PPAR𝜶/APOE4 pathway [PDF]
We investigated the anti-aging effects of velvet antler polypeptide on D-galactose (D-gal)-induced aging mice. D-gal-induced aging mice were established and randomly divided into five groups, the control, model, vitamin E (VE), velvet antler ...
Xiaoran Liu +14 more
doaj +1 more source
Velvet antler water extract protects porcine oocytes from lipopolysaccharide-induced meiotic defects. [PDF]
AbstractPrevious studies have demonstrated that lipopolysaccharide (LPS), as a central toxic factor of gram‐negative bacteria, can induce oxidative stress and cellular inflammation to result in the impairment of female fertility in different organisms.
Chen J +8 more
europepmc +3 more sources
RNA sequencing-based identification of microRNAs in the antler cartilage of Gansu red deer (Cervus elaphus kansuensis) [PDF]
Background The velvet antler is a complex mammalian bone organ with unique biological characteristics, such as regeneration. The rapid growth stage (RGS) is a special period in the regeneration process of velvet antler. Methods To elucidate the functions
Yanxia Chen +5 more
doaj +2 more sources

