Results 1 to 10 of about 165,103 (361)

SARS-CoV-2 infection in free-ranging white-tailed deer

Nature, 2021
Humans have infected a wide range of animals with SARS-CoV-21–5, but the establishment of a new natural animal reservoir has not been observed. Here we document that free-ranging white-tailed deer (Odocoileus virginianus) are highly susceptible to ...
Vanessa L. Hale, P. Dennis, D. McBride, J. Nolting, Christopher Madden, D. Huey, Margot Ehrlich, J. Grieser, J. Winston, Dusty Lombardi, Stormy Gibson, Linda Saif, M. Killian, K. Lantz, Rachel M. Tell, M. Torchetti, S. Robbe-Austerman, M. Nelson, S. Faith, A. Bowman   +19 more
semanticscholar   +1 more source

Network Pharmacology, Molecular Docking and Molecular Dynamics to Explore the Potential Immunomodulatory Mechanisms of Deer Antler

International Journal of Molecular Sciences, 2023
The use of deer antlers dates back thousands of years in Chinese history. Deer antlers have antitumor, anti-inflammatory, and immunomodulatory properties and can be used in treating neurological diseases.
Lingyu Liu, Yu Jiao, Mei Yang, Lei Wu, Guohui Long, Wei Hu   +5 more
semanticscholar   +1 more source

Transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States

Nature Communications, 2023
SARS-CoV-2 is a zoonotic virus with documented bi-directional transmission between people and animals. Transmission of SARS-CoV-2 from humans to free-ranging white-tailed deer (Odocoileus virginianus) poses a unique public health risk due to the ...
Aijing Feng, S. Bevins, Jeffrey C. Chandler, T. Deliberto, R. Ghai, K. Lantz, J. Lenoch, A. Retchless, S. Shriner, Cynthia Y. Tang, S. Tong, M. Torchetti, A. Uehara, Xiu-Feng Wan   +13 more
semanticscholar   +1 more source

N-Succinyl-S-Farnesyl-L-Cysteine (SFC): A Novel Isoprenylcysteine Analog with In Vitro Anti-Inflammatory Activity and Clinical Skin Protecting Properties

Cosmetics, 2021
Over the past 15 years, small molecule isoprenylcysteine (IPC) analogs have been identified as a potential new class of topical anti-inflammatories. Clinical studies have demonstrated that IPCs are both safe and effective in promoting healthy skin when ...
José R. Fernández, Karl Rouzard, Corey Fitzgerald, Jason Healy, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Maxwell Stock, Eduardo Pérez   +8 more
doaj   +1 more source

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance The results provide strong evidence of extensive SARS-CoV-2 infection of white-tailed deer, a free-living wild animal species with widespread distribution across North, Central, and South America.
S. Kuchipudi, Meera Surendran-Nair, R. Ruden, Michele Yon, R. Nissly, K. Vandegrift, R. Nelli, Ling-ling Li, B. Jayarao, C. Maranas, Nicole Levine, Katriina Willgert, A. Conlan, R. Olsen, James J. Davis, J. Musser, P. Hudson, V. Kapur   +17 more
semanticscholar   +1 more source

Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in Pseudomonas aeruginosa

Antibiotics, 2021
The ability to rescue the activity of antimicrobials that are no longer effective against bacterial pathogens such as Pseudomonas aeruginosa is an attractive strategy to combat antimicrobial drug resistance.
Yi Yuan, Jesus D. Rosado-Lugo, Yongzheng Zhang, Pratik Datta, Yangsheng Sun, Yanlu Cao, Anamika Banerjee, Ajit K. Parhi   +7 more
doaj   +1 more source

Deer

, 2016
GPS locations of four black-tailed deer tracked for approximately seven months. Four columns: id, date, x,
Chamaillé-Jammes, Simon, Simon Chamaillé-Jammes (390565), Riotte-Lambert, Louise, Simon Benhamou (128619), Louise Riotte-Lambert (3201033), Benhamou, Simon   +5 more
openaire   +2 more sources

Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission

Nature Microbiology, 2022
Wildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral variants that can emerge to infect humans. In North America, there is phylogenomic evidence of continual transmission of severe acute respiratory syndrome ...
Brad Pickering, Oliver Lung, F. Maguire, Peter Kruczkiewicz, Jonathon D. Kotwa, T. Buchanan, M. Gagnier, J. Guthrie, C. Jardine, A. Marchand-Austin, A. Massé, Heather McClinchey, K. Nirmalarajah, P. Aftanas, J. Blais-Savoie, Hsien-Yao Chee, Emily A. Chien, W. Yim, Andra Banete, B. Griffin, L. Yip, M. Goolia, M. Suderman, M. Pinette, Greg A. Smith, Daniel Sullivan, Josip Rudar, Oksana Vernygora, E. Adey, Michelle Nebroski, Guillaume Goyette, A. Finzi, G. Laroche, A. Ariana, Brett Vahkal, M. Côté, A. McGeer, L. Nituch, S. Mubareka, J. Bowman   +39 more
semanticscholar   +1 more source

SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus)

Proceedings of the National Academy of Sciences of the United States of America, 2021
Widespread human SARS-CoV-2 infections combined with human–wildlife interactions create the potential for reverse zoonosis from humans to wildlife. We targeted white-tailed deer (Odocoileus virginianus) for serosurveillance based on evidence these deer ...
J. Chandler, S. Bevins, Jeremy W. Ellis, Timothy J Linder, Rachel M. Tell, M. Jenkins-Moore, J. Root, J. Lenoch, S. Robbe-Austerman, T. Deliberto, T. Gidlewski, Mia Kim Torchetti, S. Shriner   +12 more
semanticscholar   +1 more source

Accelerated evolution of SARS-CoV-2 in free-ranging white-tailed deer

Research Square, 2023
While SARS-CoV-2 has sporadically infected a wide range of animal species worldwide1, the virus has been repeatedly and frequently detected in white-tailed deer in North America2–7.
D. McBride, Sofya K. Garushyants, John Franks, Andrew F. Magee, Steven Overend, D. Huey, A. Williams, S. Faith, A. Kandeil, Sanja Trifkovic, Lance Miller, T. Jeevan, Anami R. Patel, J. Nolting, M. Tonkovich, J. T. Genders, Andrew J. Montoney, Kevin Kasnyik, Timothy J Linder, S. Bevins, J. Lenoch, J. Chandler, T. Deliberto, E. Koonin, M. Suchard, P. Lemey, R. Webby, M. Nelson, A. Bowman   +28 more
semanticscholar   +1 more source