Results 51 to 60 of about 62,274 (261)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Kajian Arahan Penyediaan Ruang Kota Bagi Pedagang Kaki Lima di Kawasan Pendidikan Tembalang, Kota Semarang

open access: yesJurnal Pembangunan Wilayah dan Kota, 2017
Street vendors (PKL) are one of the informal sectors that are often viewed as a parasite sector and have a negative impact on the city's image. However, the existence of street vendors also become one of the highest city's economic support and provide ...
Nur Khasanah Apriliasari
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Street pulse: Unveiling the health mosaic – exploring physical health, mental wellness, and quality of life among street vendors

open access: yesJournal of Education and Health Promotion
BACKGROUND: In India, street vending remains an essential aspect of the informal economy as it serves as a source of employment and opportunities for livelihood to a substantial portion of the population. This study aimed to evaluate the physical health,
H Gladius Jennifer, Sambasivam Indra
doaj   +1 more source

Formalisasi Aktivitas Pedagang Kaki Lima di Simpanglima Semarang

open access: yesJurnal Pembangunan Wilayah dan Kota, 2013
Semarang City is one of the cities that are currently paying more attention to the informal sector especially street vendors (PKL-Pedagang Kaki Lima). The government attentions has been formulated as policy in form of street vendor’s arrangement program,
Octora Lintang Surya
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

VENDOR’S PERCEPTION ABOUT ONLINE FOOD DELIVERY PLATFORMS

open access: yesICTACT Journal on Management Studies
The purpose of this study was to determine vendor’s perception about using an online food delivery platform (third-party aggregators’ operations). The objectives of the research are to find the factors that influence vendors’ decisions to use online food
K. Rajamani   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

"OPIUM ANTIDOTES," AND THEIR VENDORS. [PDF]

open access: yesJournal of the American Medical Association, 1886
If aught were asked for as to further proof of the widespread extent of opium addiction in this country, it could easily be given by citing the number of individuals engaged in vending the various nostrums, each of which, it is asserted, has the only true claim to merit as the one genuine, sovereign cure for this phase of human ill.
openaire   +2 more sources

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