From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Influence of Synthetic Fibers Angle Orientation on Bending Properties of Composite Plywood
This paper presents the results of research on carbon fiber angle orientation and quantity of carbon fi bers in yarn on bending properties of plywood. For that purpose the specimens have been defined as multilayer composites made from carbon fibers and ...
Mladen Brezović +3 more
doaj
In this research the spruce plywood board and combined spruce-beech plywood board were prepared in laboratory conditions using two levels of processing pressure.
P. Král, P. Klímek
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Commodity risk assessment of maple veneer sheets from Canada
The European Commission requested the EFSA Panel on Plant Health to deliver a risk assessment on the likelihood of pest freedom from Union quarantine pests and pests subject to measures adopted pursuant to Article 30 of Regulation (EU) No 2016/2031 for ...
EFSA Panel on Plant Health (PLH) +29 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
ASSESSMENT ON ANATOMICAL AND PHYSICO-MECHANICAL PROPERTIES OF GROWN NEWBOULDIA LAEVIS (P. BEAUV.) AND ANINGERIA ROBUSTA (AUBREV. AND PELLEGR.) IN NIGERIA FOR UTILIZATION POTENTIALS [PDF]
Nigerian grown Newbouldia laevis and Aningeria robusta were investigated in this study. The densities of the wood at the green condition and 12% moisture content were assessed.
Ogunleye M.B., Aina K.S., Adeniyi I.M.
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Properties of Veneer and Veneer-Based Products from Genetically Improved White Spruce Plantations [PDF]
This study examined the suitability of genetically improved fast-growing and short-rotation plantations for veneer-based products. The materials came from a 36-year-old white spruce (Picea glauca) half-sib progeny/provenance trial located in two regions (
Wang, Brad J. +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

