Results 71 to 80 of about 6,134 (242)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Determination of the pressing parameters of spruce water-resistant plywood

open access: yesJournal of Forest Science, 2007
The paper summarizes results of operations aimed at determining the pressing parameters of spruce water-resistant plywood and testing the suitability of particular constructions of plywood. Constant and variable parameters were determined.
J. Hrázský, P. Král
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Assessing the bending strength and modulus of elasticity in bending of exterior foiled plywoods in relation to their construction

open access: yesJournal of Forest Science, 2005
The paper summarizes results of an institutional research aimed at assessing the bending strength and modulus of elasticity in bending of exterior foiled combined and all-beech plywoods in relation to their construction. A relationship was studied of the
J. Hrázský, P. Král
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The state of the tooth pulp, prepared for veneers

open access: yesЭндодонтия Today, 2020
The pulp reaction was studied for preparation and fixation of veneers with the help of the electronic pulp test device IVN-01 Pulptest Pro. Veneers were installed in 109 patients, the average age was 31,40 ± 3,51 years.

doaj  

Colour Changes Evaluation of Freshly Cut Alder Veneers Under the Influence of Indoor Sunlight [PDF]

open access: yesPro Ligno, 2011
The paper presents an experimental study concerning the colour changes occurred on the surfaces ofblack alder veneers (Alnus glutinosa), obtained from a freshly cut (not treated) log, after their exposure tosunlight and darkness, for 1 and 3 months ...
Emilia Adela SALCA
doaj  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

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