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Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina+9 more
wiley +1 more source
Chronic Venous Insufficiency [PDF]
Nearly every second adult in Europe suffers from ve- nous disorders. In only 15% are they considered to be venous diseases threatening the patient. The spectrum ranges from spider telangiectasia to chronic states and acute, potentially lethal, pulmonary embolism — generally described as chronic venous in- sufficiency (CVI).
openaire +4 more sources
Lipodermatosclerosis and diabetic dermopathy are low-risk skin lesions with many similar clinical features, except for venous abnormalities such as chronic venous insufficiency, but are rarely a reason for referring the patient to vascular ultrasound ...
Podoleanu Cristian+3 more
doaj +1 more source
BACKGROUND: Ultrasound-guided foam sclerotherapy plays a major role in treatment of chronic venous insufficiency, providing clinical and hemodynamic improvement to patients undergoing treatment.OBJECTIVES: To examine the relationships between venous ...
Felipe Coelho Neto+2 more
doaj +1 more source
A systematic review of cost-effectiveness analyses of complex wound interventions reveals optimal treatments for specific wound types. [PDF]
BackgroundComplex wounds present a substantial economic burden on healthcare systems, costing billions of dollars annually in North America alone.
Antony, Jesmin+7 more
core +3 more sources
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
Background: Venoplasty and stenting is a minimally invasive therapy that can be used for patients with deep venous insufficiency in the lower extremities.
Majid Moeini+9 more
doaj
What is a venous duplex study anyway? Redefining ultrasound protocols in modern venous practice
Introduction: Venous duplex ultrasound (VDU) is the diagnostic standard for deep venous thrombosis (DVT); however, modern venous practice requires information for a variety of other venous disorders.
M Angelson, Douglas L Wooster
doaj +1 more source
Chronic dermatomycoses of the foot as risk factors for acute bacterial cellulitis of the leg: A case-control study [PDF]
Objective: To assess the role of foot dermatomycosis ( tinea pedis and onychomycosis) and other candidate risk factors in the development of acute bacterial cellulitis of the leg.
Bardur Sigurgeirsson+13 more
core +1 more source
Chronic Cerebrospinal Venous Insufficiency
Dear Editor: I read with interest the article published by Kugler et al. [1]. Regarding the duplex ultrasound examination the author didn’t consider the paper by Zamboni et al. [2] published in December 2011 on international angiology. In this document the authors noted that a high prevalence ranging from 62% to 100% of obstructive lesions has ...
openaire +3 more sources