Results 181 to 190 of about 92,093 (263)

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

Advanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan, Yuling Xu, Ting Yu, Yang Li, Xin Jiang, Haoyu Jin, Haitao Li, Youyu Zhang, Peng Yin, Jong Seung Kim   +9 more
wiley   +1 more source

Analysis of the Combined Effects of a Novel Combination of Hypersmin, Pumpkin Seed and Amaranthus Extracts in an In Vitro Model of Chronic Venous Insufficiency. [PDF]

Nutrients
Ferrari S, Galla R, Mulè S, Molinari C, Uberti F.   +4 more
europepmc   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

Nutritional Status in a Group of Patients with Wounds Due to Diabetic Foot Disease and Chronic Venous Insufficiency. [PDF]

J Clin Med
Skórka M, Bazaliński D, Więch P, Kłęk S, Kozieł D, Sierżantowicz R.   +5 more
europepmc   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Single-leaflet reconstruction surgery for severe chronic lower limb venous insufficiency caused by post-thrombotic syndrome: a case report and literature review. [PDF]

Thromb J
Liu D, Zhao H, Zhang J, Zhao L, Wu Y.
europepmc   +1 more source

Low‐Field Giant Dielectric Tunability by Polaron‐Mediated Interfacial Polarization in Pulsed‐Laser‐Deposited‐Nanocrystalline/Amorphous Composite BaTiO3 Thin Films

Advanced Electronic Materials, EarlyView.
Comparison of tunability efficiency between vacuum‐deposited PLD‐BTO films grown at Td = 550°C in the present study and representative previous reports. ABSTRACT Electrically tunable dielectric thin films are essential components for next‐generation low‐voltage electronic devices.
Shinya Kondo, Taichi Murakami, Loick Pichon, Joël Leblanc‐Lavoie, Takashi Teranishi, Akira Kishimoto, Tomoaki Yamada, My Ali El Khakani   +7 more
wiley   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

Omics Data Integration Uncovers mRNA-miRNA Interaction Regions in Genes Associated with Chronic Venous Insufficiency. [PDF]

Genes (Basel)
Sarı-Tunel F, Demirkan A, Vural B, Yıldız CE, Komurcu-Bayrak E.   +4 more
europepmc   +1 more source