Results 261 to 270 of about 137,225 (329)

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

Advanced chronic venous insufficiency and the role of the incompetent perforator vein: A 100-year quest for the right strategy. [PDF]

J Vasc Surg Cases Innov Tech
Jayaraj A.
europepmc   +1 more source

A Bioinstructive Injectable Hydrogel for Enhancing Intrinsic Regeneration through Cell Recruitment and Training

Advanced Science, EarlyView.
A bioinstructive injectable hydrogel enables sustained release of stromal cell–derived factor‐1 alpha (SDF‐1α) and stable retention of laminin through ionic and hydrophobic interactions. This dual‐signaling matrix promotes endogenous stem cell recruitment and training, supports angiogenesis, and enhances intrinsic regenerative processes in ischemic ...
Yurim Kim, Young‐Min Kim
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Chronic venous insufficiency, could it be one of the missing pieces in the puzzle of treating pain? [PDF]

World J Clin Cases
Chang MC.
europepmc   +1 more source

Human intestinal and multivisceral transplantation [PDF]

, 1994
Abu-Elmagd, K, Cillo, U, Fung, JJ, Furukawa, H, Marino, IR, Scotti-Foglieni, CL, Starzl, TE, Todo, S, Tzakis, A   +8 more
core  

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Treatment and rehabilitation of ankle fractures in patients with chronic venous insufficiency

Yuliia Filiak, U.V. Kuz, І. М. Гудз, Roman Bihun, V.P. Omelchuk, T.I. Mulyk, Maksym P. Fedyniak, Bohdan Divnych, S. M. Vasyliuk, Vadym Sulyma   +9 more
openalex   +2 more sources

Plasma concentration of selected biochemical markers of endothelial dysfunction in women with various severity of chronic venous insufficiency (CVI)—A pilot study

, 2018
Magdalena Budzyń, Maria Iskra, Wojciech Turkiewicz, Zbigniew Krasiński, Bogna Gryszczyńska, Magdalena Paulina Kasprzak   +5 more
openalex   +2 more sources

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

Advanced Science, EarlyView.
This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu, Xin Cui, Shanshan Liu, Lu Gao, Yingang Sun, Yujun Chen, Mianlong Li, Yuxin Fan, Jing Kuang, Wen Song, Feifan Zhou   +10 more
wiley   +1 more source