Results 11 to 20 of about 14,537 (193)

Longitudinal Evaluation of Biomarkers in Wound Fluids from Venous Leg Ulcers and Split-thickness Skin Graft Donor Site Wounds Treated with a Protease-modulating Wound Dressing

Acta Dermato-Venereologica, 2022
Venous leg ulcers represent a clinical challenge and impair the quality of life of patients. This study examines impaired wound healing in venous leg ulcers at the molecular level.
Jacek Mikosiński, Konstantinos Kalogeropoulos, Louise Bundgaard, Cathrine Agnete Larsen, Simonas Savickas, Aleksander Moldt Haack, Konrad Pańczak, Katarzyna Rybołowicz, Tomasz Grzela, Michał Olszewski, Piotr Ciszewski, Karina Sitek-Ziółkowska, Krystyna Twardowska-Saucha, Marek Karczewski, Daniel Rabczenko, Agnieszka Segiet, Patrycja Buczak-Kula, Erwin M. Schoof, Sabine A. Eming, Hans Smola, Ulrich auf dem Keller   +20 more
doaj   +1 more source

Photobiomodulation, as additional treatment to traditional dressing of hard-to-heal venous leg ulcers, in frail elderly with municipality home healthcare

PLoS ONE, 2022
The main objectives of the study were to explore whether laser Photobiomodulation (PBM) in addition to traditional dressing of hard-to-heal venous leg ulcer, reduced healing time of the ulcer and if the duration of the ulcer before PBM impacted the ...
Marianne Degerman, Micael Öhman, Bo C. Bertilson   +2 more
doaj   +2 more sources

Compression for venous leg ulcers [PDF]

Cochrane Database of Systematic Reviews, 2012
Up to one percent of people in industrialised countries will suffer from a leg ulcer at some time. The majority of these leg ulcers are due to problems in the veins, resulting in an accumulation of blood in the legs. Leg ulcers arising from venous problems are called venous (or varicose or stasis) ulcers. The main treatment is the application of a firm
O'Meara, Susan, Cullum, Nicky; id_orcid 0000-0003-2631-123X, Nelson, E. Andrea, Dumville, J. C.; id_orcid 0000-0002-6546-3685   +3 more
openaire   +3 more sources

Venous Leg Ulcers.

American family physician, 2016
Leg ulcers usually occur secondary to venous reflux or obstruction, but 20% of people with leg ulcers have arterial disease, with or without venous disorders. Between 1.5 and 3.0 in 1000 people have active leg ulcers. Prevalence increases with age to about 20 in 1000 people aged over 80 years.We conducted a systematic overview, aiming to answer the ...
Nelson, EA, Adderley, U
  +12 more sources

Can Wound Exudate from Venous Leg Ulcers Measure Wound Pain Status?: A Pilot Study. [PDF]

PLoS ONE, 2016
We investigated the associations between the self-evaluated pain status and two pain biomarker candidates, nerve growth factor and S100A8/A9, in exudate from venous leg ulcer to finally develop an objective pain evaluation method.
Taichi Goto, Nao Tamai, Gojiro Nakagami, Aya Kitamura, Ayumi Naito, Masayuki Hirokawa, Chisako Shimokawa, Kazuo Takahashi, Junichi Umemoto, Hiromi Sanada   +9 more
doaj   +1 more source

A randomised controlled trial of compression therapies for the treatment of venous leg ulcers (VenUS 6): study protocol for a pragmatic, multicentre, parallel-group, three-arm randomised controlled trial

Trials, 2023
Background Venous leg ulcer(s) are common, recurring, open wounds on the lower leg, resulting from diseased or damaged leg veins impairing blood flow. Wound healing is the primary treatment aim for venous leg ulceration, alongside the management of pain,
C. E. Arundel, C. Welch, P. Saramago, U. Adderley, R. Atkinson, I. Chetter, N. Cullum, T. Davill, J. Griffiths, C. Hewitt, C. Hirst, M. Kletter, J. Mullings, G. Roberts, B. Smart, M. Soares, P. Stather, L. Strachan, N. Stubbs, D. J. Torgerson, J. Watson, S. Zahra, J. Dumville   +22 more
doaj   +1 more source

Clinico-etiological evaluation of chronic leg ulcer in a tertiary care center of eastern India

Indian Journal of Dermatology, 2020
Background: A chronic leg ulcer (CLU) is a significant public health problem. It has various etiologies. Racial, familial, occupational, and social factors may also have an impact on the prevalence of different causes of leg ulcers.
Falguni Nag, Gobinda Chatterjee, Arghyaprasun Ghosh, Abhishek De   +3 more
doaj   +1 more source

Role of Platelet Rich Plasma in Healing of Chronic Venous Leg Ulcer: A Randomized Controlled Clinical Trial [PDF]

Ain Shams Medical Journal, 2023
Background: Venous ulcers leg account for 80% of leg wounds caused by chronic venous insufficiency. Autologous platelet-rich plasma is used for wound healing treatment as it contains great variety of growth factors.
Mohammed Badr, Reda Ezz, Ayman Abdelmonaem, Amr Kamel   +3 more
doaj   +1 more source

Debridement for venous leg ulcers [PDF]

Cochrane Database of Systematic Reviews, 2010
Background Venous ulcers (also known as varicose or venous stasis ulcers) are a chronic, recurring and debilitating condition that affects up to 1% of the population. Best practice documents and expert opinion suggests that the removal of devitalised tissue from venous ulcers (debridement) by any one of six methods helps to promote healing. However, to
Gethin, Georgina, Cowman, Seamus, Kolbach, Dinanda N.   +2 more
openaire   +2 more sources

Venous and arterial leg ulcers [PDF]

BMJ, 2006
Venous leg ulceration is due to sustained venous hypertension, which results from chronic venous insufficiency. In the normal venous system, pressure decreases with exercise as a result of the action of the calf muscle pump. When the muscles relax, the valves in the perforating veins connecting the superficial to the deep venous circulation prevent ...
Joseph E, Grey, Keith G, Harding, Stuart, Enoch   +2 more
openaire   +2 more sources