Results 21 to 30 of about 475,313 (268)

Atrial amyloidosis: mechanisms and clinical manifestations

European Journal of Heart Failure, Volume 24, Issue 11, Page 2019-2028, November 2022., 2022
Atrial amyloidosis: pathophysiology and clinical manifestations. Atrial amyloidosis can manifest as part of a systemic disorder (as in amyloid light‐chain [AL] or transthyretin [ATTR] amyloidosis), or be isolated (in the form due to atrial natriuretic type [ANP] accumulation); this last form is often associated with permanent or persistent atrial ...
Giuseppe Vergaro, Alberto Aimo, Claudio Rapezzi, Vincenzo Castiglione, Iacopo Fabiani, Angela Pucci, Gabriele Buda, Claudio Passino, Josep Lupón, Antoni Bayes‐Genis, Michele Emdin, Eugene Braunwald   +11 more
wiley   +1 more source

Inflammation, Infection and Venous Thromboembolism.

Circulation Research, 2021
The association between inflammation, infection, and venous thrombosis has long been recognized; yet, only in the last decades have we begun to understand the mechanisms through which the immune and coagulation systems interact and reciprocally regulate ...
M. Colling, Benjamin E. Tourdot, Y. Kanthi   +2 more
semanticscholar   +1 more source

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
Neutrophils play a role in the immunopathology SARS‐CoV‐2 infection by triggering the formation of NETs, producing cytokines including interleukin‐8 (CXCL8), and mediating the recruitment of other immune cells to regulate inflammation, which can lead to ARDS.
Maria Candida Cesta, Mara Zippoli, Carolina Marsiglia, Elizabeth M. Gavioli, Giada Cremonesi, Akram Khan, Flavio Mantelli, Marcello Allegretti, Robert Balk   +8 more
wiley   +1 more source

Opto-UNet: Optimized UNet for Segmentation of Varicose Veins in Optical Coherence Tomography [PDF]

, 2023
Human veins are important for carrying the blood from the body-parts to the heart. The improper functioning of the human veins may arise from several venous diseases. Varicose vein is one such disease wherein back flow of blood can occur, often resulting in increased venous pressure or restricted blood flow due to changes in the structure of vein.
arxiv   +1 more source

SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

Anaesthesia, 2021
SARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients ...
Ian Shyaka
semanticscholar   +1 more source

Warfarin dose estimation on multiple datasets with automated hyperparameter optimisation and a novel software framework [PDF]

Journal of Biomedical Informatics, 2020, 2019
Warfarin is an effective preventative treatment for arterial and venous thromboembolism, but requires individualised dosing due to its narrow therapeutic range and high individual variation. Many machine learning techniques have been demonstrated in this domain.
arxiv   +1 more source

Isatuximab plus carfilzomib and dexamethasone versus carfilzomib and dexamethasone in elderly patients with relapsed multiple myeloma: IKEMA subgroup analysis

Hematological Oncology, Volume 40, Issue 5, Page 1020-1029, December 2022., 2022
Abstract In this subgroup analysis of the randomized, Phase 3 IKEMA study (NCT03275285), we evaluated efficacy and safety of the anti‐CD38 monoclonal antibody isatuximab (Isa) in combination with carfilzomib‐dexamethasone (Isa‐Kd) versus Kd in older (≥70 years of age, n = 86) and younger (<70 years, n = 216) patients with relapsed multiple myeloma (MM).
Thierry Facon, Philippe Moreau, Thomas G. Martin, Ivan Spicka, Albert Oriol, Youngil Koh, Andrew Lim, Gabor Mikala, Laura Rosiñol, Münci Yağci, Michele Cavo, Kwee Yong, Marie‐Laure Risse, Gaëlle Asset, Sandrine Schwab, Gracia Martinez   +15 more
wiley   +1 more source

Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors

Journal of Thrombosis and Thrombolysis, 2020
Coagulopathy in COVID-19 is a burning issue and strategies to prevent thromboembolic events are debated and highly heterogeneous. The objective was to determine incidence and risk factors of venous thromboembolism (VTE) in COVID-19 inpatients receiving ...
M. Artifoni, G. Danic, G. Gautier, Pascal Gicquel, D. Boutoille, F. Raffi, A. Néel, R. Lecomte   +7 more
semanticscholar   +1 more source

The epidemiology of venous thromboembolism [PDF]

Journal of Thrombosis and Thrombolysis, 2016
Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis ...
Richard H. White, Frederick A. Spencer, John A. Heit   +2 more
openaire   +2 more sources

SurvLatent ODE : A Neural ODE based time-to-event model with competing risks for longitudinal data improves cancer-associated Venous Thromboembolism (VTE) prediction [PDF]

arXiv, 2022
Effective learning from electronic health records (EHR) data for prediction of clinical outcomes is often challenging because of features recorded at irregular timesteps and loss to follow-up as well as competing events such as death or disease progression.
arxiv