Results 61 to 70 of about 101,068 (248)

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Hyperhomocysteinemia is associated with the risk of venous thromboembolism in patients with mental illness: a case-control study

Frontiers in Psychiatry
ObjectiveThe risk of venous thromboembolism in patients with mental illness has been insufficiently addressed. This study aimed to assess the correlation between hyperhomocysteinemia and venous thromboembolism prevalence among this population ...
Jiaoyan Wang, Jiaoyan Wang, Yingchun Zhang, Keming Ren, Yeping Li, Kejing Ying   +5 more
doaj   +1 more source

High Incidence of Postoperative Silent Venous Thromboembolism in Ulcerative Colitis [PDF]

, 2021
Norimitsu Shimada, Hiroki Ohge, Hiroki Kitagawa, Kosuke Yoshimura, Norifumi Shigemoto, Yusuke Watadani, Shinnosuke Uegami, Kenichiro Uemura, Shin’ya Takahashi   +8 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source

Pulmonary thromboembolism in a patient with myotonic dystrophy type 1

Annals of Indian Academy of Neurology, 2012
Thromboembolism is a rare complication in patients with myotonic dystrophy. While immobilization of patients with advanced disease predisposes to high risk for venous thromboembolism, hypercoagulability could account for venous thromboembolism in ...
Joong-Yang Cho, So-Young Seo, Yong-Jin Cho, Keun-Sik Hong, Hee Kyung Park, Ju Hyun Lee, Sung-Soon Lee   +6 more
doaj   +1 more source

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

International Journal of Cancer, EarlyView.
What's New? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander, Alessandra I. G. Buma, Jenneke Leentjens, Paddy K. C. Janssen, Michel M. van den Heuvel, David M. Burger, Berber Piet, Rob ter Heine   +7 more
wiley   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Ambulatory Portable Pneumatic Compression Device as Part of a Multimodal Aspirin-Based Approach in Prevention of Venous Thromboembolism in Outpatient Total Knee Arthroplasty [PDF]

, 2020
David A. Crawford, Richard L. Andrews, Michael J. Morris, Jason M. Hurst, Adolph V. Lombardi, Keith R. Berend   +5 more
openalex   +1 more source

Cardiovascular risk profile according to World Health Organization medical eligibility criteria for contraceptive use of women using hormonal contraception in Rio de Janeiro state, Brazil

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Hormonal contraception, especially combined oral contraceptives, is associated with an increase in cardiovascular risk. Thus, we aimed to analyze the use of hormonal contraceptive methods in the state of Rio de Janeiro (Brazil), with a focus on determining whether contraceptive use follows the cardiovascular profile of women ...
Isabela Pereira Fonseca Brusth, Juliana Montani Raimundo, Helene Nara Henriques Blanc   +2 more
wiley   +1 more source