Results 121 to 130 of about 3,345,378 (306)

Comprehensive ventilation/perfusion SPECT

open access: yes, 2001
Lung scintigraphy is the primary tool for diagnostics of pulmonary embolism. A perfusion study is often complemented by a ventilation study. Intermediate probability scans are frequent.
Jonson, Björn   +3 more
core  

Dead-space ventilation as a determinant in the ventilation-perfusion concept

open access: yes, 1960
Gas exchange in an alveolus is affected by the redistribution of dead-space gas during inspiration. Theoretical analysis of the total ventilation of an alveolus permits the description of several new concepts.
Benjamin B. Ross, Leon E. Farhi
core   +1 more source

From Physiology to Bioheat Simulation: A Data‐Driven Framework for Core Temperature Initialization

open access: yesHeat Transfer, EarlyView.
ABSTRACT Accurate initialization of core body temperature is a critical yet often overlooked component of bioheat transfer models, particularly when such models are applied to heterogeneous populations and real‐world environmental conditions. Conventional bioheat simulations typically rely on fixed or idealized core body temperature values derived from
David S. Rodríguez   +6 more
wiley   +1 more source

Effects of Single and Multiple Dose Tiotropium/Olodaterol in Chronic Obstructive Pulmonary Disease on Alveolar Gas Exchange Measured by Hyperpolarized 129Xe MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Long‐acting muscarinic antagonists/long‐acting beta adrenoreceptor agonists lead to lung deflation and improved microvascular perfusion in hyperinflated chronic obstructive pulmonary disease (COPD), but with an unclear time course. Purpose To investigate the effect of inhalation of tiotropium/olodaterol (TIO/OLO) on MRI measures of ...
Agilo L. Kern   +7 more
wiley   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao   +6 more
wiley   +1 more source

Changes in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling

open access: yes, 2018
Bita Hajian,1 Jan De Backer,2 Wim Vos,2 Wouter H van Geffen,3 Paul De Winter,1 Omar Usmani,4 Tony Cahn,5 Huib AM Kerstjens,3 Massimo Pistolesi,6 Wilfried De Backer1 1Department of Respiratory Medicine, University Hospital Antwerp, Edegem, Belgium ...
Pistolesi M   +9 more
core  

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si   +3 more
wiley   +1 more source

Lung ventilation/perfusion SPECT in the artificially embolized pig.

open access: yes, 2002
Planar lung scintigraphy is a standard method used for the diagnosis of lung embolism, but it is hampered by the high incidence of nondiagnostic tests. Ventilation/perfusion SPECT may possibly improve this situation.
Jonson, Björn   +5 more
core   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

open access: yesThe Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz   +7 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

open access: yesMed Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu   +9 more
wiley   +1 more source

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