Results 131 to 140 of about 3,345,378 (306)

QQ‐Based Oxygen Extraction Fraction (OEF) Mapping in Mouse Brain: Initial Experience

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Oxygen extraction fraction (OEF) is a vital biomarker of cerebral oxygen metabolism and tissue viability. A novel OEF mapping method, QQ, which combines quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent (qBOLD) (QSM + qBOLD = QQ), has demonstrated promise in detecting disease‐related OEF ...
Quinn Boyer   +4 more
wiley   +1 more source

Independent Component Analysis for Non‐Contrast‐Enhanced Free‐Breathing Pulmonary Ventilation and Perfusion MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To introduce a robust approach for non‐contrast‐enhanced free‐breathing functional lung MRI based on independent component analysis (ICA), addressing key limitations of standard methods such as sensitivity to irregular breathing or irregular heartbeat.
Laura Rozo Pardo   +8 more
wiley   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Breathless on Standing: Hepatopulmonary Syndrome in Chronic Liver Disease

open access: yesAnnals of Internal Medicine: Clinical Cases
In patients with chronic liver disease, positional dyspnea (platypnea) and desaturation (orthodeoxia) should prompt immediate evaluation. Although the differential diagnosis includes many cardiopulmonary disorders, platypnea-orthodeoxia raises concern ...
Kamel Alachraf   +2 more
doaj   +1 more source

Impaired matching of perfusion and ventilation in heart failure detected by 133xenon

open access: yes, 1996
In severe chronic heart failure (CHF) the ventilatory cost of CO2 elimination during exercise (VE/VCO 2) is increased, suggesting ventilation/perfusion (V/Q) mismatch.
Evans, W. D.   +13 more
core   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

open access: yesRheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina   +3 more
wiley   +1 more source

Enhanced glomerular thrombosis in pronated animals with ARDS

open access: yesIntensive Care Medicine Experimental
Background Prone positioning is part of the management of acute respiratory distress syndrome (ARDS) and has been demonstrated to successfully improve the ventilation–perfusion match and reduce mortality in patients with severe respiratory failure ...
Silvia Marchesi   +6 more
doaj   +1 more source

Intelligent Continuum Micromachines in Complex Confined Spaces

open access: yesSmartBot, EarlyView.
The cover depicts a conceptual design for an intelligent continuum micromachine entering a target capsule used in fusion‐energy research through its slender gas‐fill tube. By combining route‐adaptive deformation, embedded sensing, and a functional end effector, the robot could inspect hidden defects, assess local conditions, and support localized ...
Huayang Sai   +7 more
wiley   +1 more source

A nomogram model based on clinical and 3D-EIT parameters for CTEPH diagnosis

open access: yesRespiratory Research
Background Chronic thromboembolic pulmonary hypertension (CTEPH) is easily misdiagnosed. Three-dimensional (3D) electrical impedance tomography (EIT) can monitor the whole-lung perfusion at the bedside.
Jian Xu   +5 more
doaj   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni   +10 more
wiley   +1 more source

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