Results 151 to 160 of about 551,358 (298)

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

Study protocol for the volume targeted mask ventilation versus pressure ventilation in preterm infants-the VOLT-trial. [PDF]

open access: yesFront Pediatr
Law BHY   +6 more
europepmc   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

open access: yesAdvanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao   +12 more
wiley   +1 more source

Exploring the effects of ventilation and air-conditioned environments, on droplet and airborne transmission of SARS-COV-2

open access: diamond, 2023
Sinan Deeb   +5 more
openalex   +2 more sources

Analysis of Multiscale Condensation Phenomena Using a Zero‐Shot Computer Vision Framework

open access: yesAdvanced Science, EarlyView.
A zero‐shot computer vision framework quantifies multiscale condensation dynamics by automatically segmenting droplets and extracting physical parameters without labeled data. The workflow integrates data mining and statistical analysis to reveal droplet growth, coalescence statistics, and sweeping behaviors, enabling label‐free measurement of heat ...
Donghyeong Lee   +5 more
wiley   +1 more source

Acute Respiratory Distress Syndrome in Patients with Intracerebral Hemorrhage. [PDF]

open access: yesJ Clin Med
Christianson T   +10 more
europepmc   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

open access: yesAdvanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen   +14 more
wiley   +1 more source

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