Results 161 to 170 of about 745,496 (300)

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Ventilation volume as a stimulus to spontaneous ventilation after prolonged artificial ventilation [PDF]

The Journal of Physiology, 1962
A C, SMITH, J M, SPALDING, W E, WATSON
openaire   +2 more sources

Relevance between patients' clinical factors and 4D-CT lung ventilation heterogeneity for evaluating the adoption of functional avoidance thoracic radiotherapy with a large patient database. [PDF]

Front Oncol
Deng G, Ying Y, Wang X, Tang X, Su S, Yu C, Gu P, Yang H.   +7 more
europepmc   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

Dynamic Xenon-Enhanced Spectral CT Imaging to Evaluate Regional Lung Function in an In Vivo Rabbit Model. [PDF]

Diagnostics (Basel)
Verelst E, Bayat S, Verbanck S, Van Gompel G, de Mey J, Buls N.   +5 more
europepmc   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Comparison of bag-valve-device ventilation and volume-controlled ventilation with laryngeal tube evo in intra-arrest ventilation-a prospective randomized study in human body donors. [PDF]

J Anesth Analg Crit Care
Falk CC, Brand-Saberi B, Förster E, Gelashvili T, Genzwürker H, Hinkelbein J, Hoyer A, Thomasseck A, Trenkel J, Tiesmeier J, Kolaparambil Varghese LJ, Jansen G.   +11 more
europepmc   +1 more source

Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

Advanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin, Jiyue Chen, Fengxin Xie, Huiyan Tian, Xuechen Dou, Yanqi Han, Lu Zhang, Jining Li, Xiang Yang   +8 more
wiley   +1 more source

Comparison of Airway-Based and Transpulmonary Mechanical Power Across Ventilation Conditions in Moderate-to-Severe ARDS. [PDF]

Life (Basel)
Soroksky A, Lianskaya A, Gingy RB, Riziny N, Goldstein AL, Tayem E, Galante O, Miller A, Tocut M.   +8 more
europepmc   +1 more source