Results 151 to 160 of about 722,543 (298)

Quantifying gravity-dependent and gravity-independent ventilation distribution by hyperpolarized ¹²⁹Xe MRI in restrictive and airway diseases. [PDF]

Front Physiol
Du KK, Mummy D, Tighe R, Que L, Driehuys B, Huang YT.   +5 more
europepmc   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Arterial cannulation site and ventilation strategy modulate cerebral injury in a rat cardiopulmonary bypass model of Harlequin syndrome. [PDF]

Intensive Care Med Exp
Aludaat C, Saiydoun G, Saade S, Baste JM, Magnan V, Doguet F, Bauer F, Bellien J, Mulder P, Besnier E.   +9 more
europepmc   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

VENTILATOR FOR INTERMITTENT MANDATORY VENTILATION

British Journal of Anaesthesia, 1978
openaire   +2 more sources

DEMAND CONTROLLED VENTILATION AND CLASSROOM VENTILATION

, 2013
This document summarizes a research effort on demand controlled ventilation and classroom ventilation. The research on demand controlled ventilation included field studies and building energy modeling. Major findings included: ? The single-location carbon dioxide sensors widely used for demand controlled ventilation frequently have large errors and ...
openaire   +2 more sources

Anesthetic Management of Tracheal Resection and Anastomosis for Postintubation Tracheal Stenosis Involving a Sequential Airway Strategy. [PDF]

Case Rep Anesthesiol
Uddin MZ, Karim M, Karim MA, Kabir MA, Ahamed H, Rahman MS, Ahmed N.   +6 more
europepmc   +1 more source

Preserving Motor Features by Alternative Re‐Referencing to Remove Heart Artifact on the Stentrode

Advanced Science, EarlyView.
Endovascular brain‐computer interfaces record neural activity from within cerebrovasculature, at the expense of electrocardiogram contamination. Band‐limited independent component analysis separates this heart‐based artifact from task‐relevant neural activity in each frequency band, enabling the reconstruction of cleaner neural recordings without the ...
Ariel K. Feldman, Kriti Kacker, Rahyun Yun, Nikole Chetty, James Bennett, Peter E. Yoo, Raul G. Nogueira, Jennifer L. Collinger, Nicholas L. Opie, Thomas J. Oxley, David F. Putrino, Douglas J. Weber   +11 more
wiley   +1 more source

Optimizing surgical site infection control systems: evaluating operating room ventilation system effectiveness in public hospitals. [PDF]

Sci Rep
Hashemi M, Mokarami H, Asadollahi A, Kim IJ, Jafari S.   +4 more
europepmc   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source