Results 91 to 100 of about 112,028 (329)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Investigation of Energy-Efficient Solutions for a Single-Family House Based on the 4E Idea in Poland

Energies
The paper analyses multi-variant energy simulations carried out in IDA ICE 4.8 software for a newly designed single-family building within the framework of the 4E Idea.
Piotr Ciuman, Jan Kaczmarczyk, Dorota Winnicka-Jasłowska   +2 more
doaj   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Coupled TRNSYS-CFD simulations evaluating the performance of PCM plate heat exchangers in an Airport Terminal building displacement conditioning system [PDF]

, 2013
This is the post-print version of the Article. The official published version can be accessed from the link below. Copyright @ 2013 Elsevier.This paper reports on the energy performance evaluation of a displacement ventilation (DV) system in an airport ...
Alauzet, Arce, Arias, Arkar, ASHRAE Standard 55-2004, Auliciems, Awbi, B.L. Gowreesunker, Bolatturk, Bryn, Chartered Institute of Building Services Engineering, Chartered Institute of Building Services Engineering, Crawley, Day, Dolado, Fan, Fanger, Gebremedhin, Goodfellow, Gousseau, Gowreesunker, Hussain, Idelchik, Kolokotroni, Leenknegt, Liu, M. Kolokotroni, Matsuia, Osterman, Parker, Ramponi, Rohdin, S.A. Tassou, Shilei, Simmonds, Simmonds, Susman, Tay, Tye-Gingras, Veluri, Voller, Zalba, Zhai, Zhai, Zhang, Zhang, Zhou   +46 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Impact of urban geometry on indoor air temperature and cooling energy consumption in traditional and formal urban environments [PDF]

, 2018
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the URI link.This study explores the effect of outdoor microclimatic environment on indoor conditions in a tropical ...
Sharmin, Tania, Steemers, Koen
core   +2 more sources

Arbitrary 3D Organic Mixed Ionic‐Electronic Conductor Architectures via Self‐Fusion of PEDOT:PSS Microfibers

Advanced Science, EarlyView.
A general fabricating strategy for arbitrary 3D organic mixed ionic‐electronic conductor architectures is reported using PEDOT:PSS microfiber building blocks. A water‐assisted self‐fusion process is successfully developed in which adhesion can be modulated as reversible (PSS‐rich) or irreversible (PEDOT‐rich) self‐fusion depending on the post‐treatment
Youngseok Kim, Jongwon Lee, Jiwoong Kim, Jung Il Yoo, Junggeon Park, Jaeyoung Lee, Heung Cho Ko, HyungJu Ahn, Myung‐Han Yoon   +8 more
wiley   +1 more source

North, South, East and West: The Environmental Approach to Transparent Design

Challenging Glass Conference Proceedings, 2010
Architecture has always been interested in transparency but this characteristic has strong implications for energy performance. For many years architecture has neglected this factor but today, in a time when society has developed an awareness of the ...
N. Baldassini
doaj   +1 more source

Post-occupancy evaluation of architecturally-designed low-income housing in Ahmadabad, India [PDF]

, 2019
This paper presents post-occupancy evaluation of low-income houses that have been built through the DMU: Square Mile India Programme in Ahmedabad, India.
Ahmad, Taki, Brabury, Simon, Sharmin, Tania, Zapata Montalvo, Luis Fernando   +3 more
core