Results 91 to 100 of about 2,245,625 (286)

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

A review of evidence linking ventillation rates in dwellings and respiratory health - a focus on house dust mites and mould [PDF]

, 2004
This paper reviews the literature for evidence of links betwen ventilation rates in dwellings and moisture related respiratory health with a particular focus on house dust mites (HDM) and fungal growth.
Ucci, M, McCarthy, M, McCarthy, M., Mumovic, D, Ridley, I., Oreszczyn, T., Ridley, I, Oreszczyn, T, Pretlove, S, Ucci, M., Davies, M, Mumovic, D., Davies, M., Singh, J., Pretlove, S., Singh, J   +15 more
core  

High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhage [PDF]

, 2010
BACKGROUND: Both high tidal volume (VT) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung injury in infant rats exposed to severe hemorrhage.
Nicholls, Philip K., Sly, P.D., Hantos, Z, Sly, Peter D., Berry, L.J., Cannizzaro, V; https://orcid.org/, Hantos, Zoltán, Cannizzaro, V., Berry, Luke J., Nicholls, P.K., Hantos, Z., Nicholls, P K, Sly, P D, Berry, L J, Cannizzaro, Vincenzo   +14 more
core   +1 more source

Development of a Hierarchical Reinforcement Learning Model for Dynamic Retail Pricing and Cooling Demand Response in Building Communities

Applied Sciences
Building cooling loads provide flexibility for demand response, but their operation must balance user cost, aggregator revenue, carbon emissions, and thermal comfort.
Xinhao Wang, Yan Gao, Zhi Sun
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

History of Intermittent Mandatory Ventilation 1971 to present. Part two

, 2022
Medical history is often overlooked as advances keep moving forward. Seldom is it that advances in medicine are truly new, unique ideas, but rather built on ideas that have been considered before.
Ronald R. Sanderson, Cheryl Rogers, Sanderson, Ron, Rogers, Cheryl   +3 more
core   +1 more source

The application of natural ventilation of residential architecture in the integrated design

IOP Conference Series: Earth and Environmental Science, 2017
As one of the important parts in the architecture design, ventilation fully reflects one important factor of energy conservation to some extent. To ensure that decreasing use of energy resources to the maximum extent in architectures and make architectures harmonize with their surroundings, which have become important pursuing gradually for residential
openaire   +1 more source

Four Truths of Mechanical Ventilation and the Ten-Fold Path to Enlightenment

, 2021
: The Four Truths 1. The truth of confusion 2. The truth of the origin of confusion 3. The truth of the cessation of confusion 4. The truth of the path leading to the cessation of confusion The 10-Fold Path 1.
Chatburn, Robert, Robert L. Chatburn
core   +1 more source

Long Term Follow-up of Ventilated Patients with Thoracic Restriction and Neuromuscular Disease

Canadian Respiratory Journal, 2002
OBJECTIVE: To evaluate the long term effects of home mechanical ventilation (HMV) on pulmonary function, nighttime gas exchange, daytime arterial blood gases, sleep architecture and functional exercise capacity (6 min walk).
Dina Brooks, James De Rosie, Margaret Mousseau, Monica Avendano, Roger S Goldstein   +4 more
doaj   +1 more source

North, South, East and West: The Environmental Approach to Transparent Design

Challenging Glass Conference Proceedings, 2010
Architecture has always been interested in transparency but this characteristic has strong implications for energy performance. For many years architecture has neglected this factor but today, in a time when society has developed an awareness of the ...
N. Baldassini
doaj   +1 more source